Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888448 | 1.00 | YAP1 (0.47) | YAP1PRMT5CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL29997809 | 0.90 | KLK7 (0.48) | KMT2AKLK7PARP1 | |
| SCHEMBL6969013 | 0.90 | KLK7 (0.48) | KMT2AKLK7PARP1 | |
| SCHEMBL19419776 | 0.84 | KLK7 (0.51) | KLK7PARP1 | |
| SCHEMBL3728443 | 0.84 | KLK7 (0.51) | KLK7PARP1 | |
| SCHEMBL15383781 | 0.84 | KLK7 (0.51) | KLK7PARP1 | |
| SCHEMBL5966655 | 0.82 | HCRTR1 (0.42) | MEN1KMT2ALMNAKLK7TP53 | |
| SCHEMBL13701096 | 0.81 | YAP1 (0.47) | YAP1PRMT5GHSRTP53 | |
| SCHEMBL5887627 | 0.80 | YAP1 (0.44) | YAP1PRMT5MEN1KMT2AKDM4C | |
| SCHEMBL598705 | 0.80 | KLK7 (0.45) | KLK7PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026335-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE CO. (US) | 2006-04-11 | — | — | US | disclosed |
| CN-1656070-A | Melanocortin receptor ligands | PROCTER & GAMBLE (US) | 2005-08-17 | — | — | CN | disclosed |
| US-20050171158-A1 | Melanocortin receptor ligands | EBETINO FRANK H (US) | 2005-08-04 | — | — | US | disclosed |
| EP-1499588-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-26 | — | — | EP | disclosed |
| US-20030236230-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2003-12-25 | — | — | US | disclosed |
| WO-2003093234-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171158-A1 | Melanocortin receptor ligands | MC1R, MC4R, MC5R | YAP1 786/4885PRMT5 489/4885CHRNB2 443/4885 |
| US-20030236230-A1 | Melanocortin receptor ligands | MC1R, MC4R, MC5R | YAP1 911/4885PRMT5 387/4885CHRNB2 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.