SCHEMBL5888752

SCHEMBL5888752

NC(C=CC(=O)O)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10944966 1.00
SCHEMBL10944954 1.00
SCHEMBL5888749 1.00
Hydrochloric Acid SCHEMBL10947905 0.98 GABRP (0.48)
Hydrochloric Acid SCHEMBL10947899 0.98 GABRP (0.48)
Hydrochloric Acid SCHEMBL10947887 0.98 GABRP (0.48)
SCHEMBL23849939 0.78
SCHEMBL10409045 0.78
SCHEMBL1225631 0.76 GABRP (0.50)
SCHEMBL8565158 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1416794-A4 REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS UNIV CHICAGO (US) 2005-06-01 EP claimed
US-20040177398-A1 Regulation of plant fertility by modulation of GABA levels in flowers CHICAGO, THE UNIVERSITY OF 2004-09-09 US claimed
EP-1416794-A2 REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS The University of Chicago (US) 2004-05-12 EP claimed
WO-2003000039-A2 REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS UNIVERSITY OF CHICAGO (US) 2003-01-03 WO claimed
CN-114867714-A Fluoro substituted cyclohexene analogues of gamma-aminobutyric acid (GABA) 西北大学 2022-08-05 CN disclosed
US-7109149-B2 Regulation of plant fertility by modulation of GABA levels in flowers THE UNIVERSITY OF CHICAGO (US) 2006-09-19 US disclosed
EP-1416794-A4 REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS UNIV CHICAGO (US) 2005-06-01 EP disclosed
US-20040177398-A1 Regulation of plant fertility by modulation of GABA levels in flowers CHICAGO, THE UNIVERSITY OF 2004-09-09 US disclosed
EP-1416794-A2 REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS The University of Chicago (US) 2004-05-12 EP disclosed
WO-2003000039-A2 REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS UNIVERSITY OF CHICAGO (US) 2003-01-03 WO disclosed
US-4528028-A Use of certain halogen-containing amino-acid compounds for controlling the growth of unwanted plants E.I. DU PONT DE NEMOURS AND COMPANY 1985-07-09 US disclosed