SCHEMBL5888955

SCHEMBL5888955

C=CCCC(=C)C(=O)OC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15519123 0.82 MAPT (0.38) ALDH1A1LMNAABCC4MAPT
SCHEMBL17182439 0.80 HSD17B10 (0.39) ALDH1A1LMNAABCC4MAPT
Maleic Acid SCHEMBL9578880 0.78 MAPT (0.39) ALDH1A1LMNAABCC4MAPT
SCHEMBL45605 0.77 MAPT (0.35) ALDH1A1LMNAABCC4MAPTKDM4E
SCHEMBL620614 0.77 MAPT (0.35) ALDH1A1LMNAABCC4MAPT
SCHEMBL5492742 0.76
SCHEMBL728980 0.75 ALDH1A1 (0.35) ALDH1A1LMNAABCC4MAPT
SCHEMBL3709138 0.75 ALDH1A1 (0.47) ALDH1A1LMNAABCC4MAPT
SCHEMBL6896365 0.75 ALDH1A1 (0.41) ALDH1A1LMNA
SCHEMBL3263975 0.73 TSHR (0.39) ALDH1A1LMNAABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005111163-A1 UV CURABLE POLYSIOLOXANE CLEARCOAT PPG INDUSTRIES OHIO, INC. (US) 2005-11-24 WO claimed
US-20040214911-A1 UV curable polysiloxane clearcoat PPG INDUSTRIES OHIO, INC. 2004-10-28 US claimed
US-7151122-B2 by actinic and/or ionizing radiation; coating of polysiloxanes or oligomers having pendant acryloyloxyalkylcarbamate or epoxyalkylcarbamate groups; such as polysiloxanes where a silicon hydride is transformed with trimethylolpropane monoallyl ether and then reacted with 2-methacryloyloxyethyl isocyanate PGG INDUSTRIES OHIO, INC. (US) 2006-12-19 US disclosed
US-7151122-B2 by actinic and/or ionizing radiation; coating of polysiloxanes or oligomers having pendant acryloyloxyalkylcarbamate or epoxyalkylcarbamate groups; such as polysiloxanes where a silicon hydride is transformed with trimethylolpropane monoallyl ether and then reacted with 2-methacryloyloxyethyl isocyanate PGG INDUSTRIES OHIO, INC. (US) 2006-12-19 US disclosed
WO-2005111163-A1 UV CURABLE POLYSIOLOXANE CLEARCOAT PPG INDUSTRIES OHIO, INC. (US) 2005-11-24 WO disclosed
WO-2005111163-A1 UV CURABLE POLYSIOLOXANE CLEARCOAT PPG INDUSTRIES OHIO, INC. (US) 2005-11-24 WO disclosed
US-20040214911-A1 UV curable polysiloxane clearcoat PPG INDUSTRIES OHIO, INC. 2004-10-28 US disclosed
US-20040214911-A1 UV curable polysiloxane clearcoat PPG INDUSTRIES OHIO, INC. 2004-10-28 US disclosed