SCHEMBL5888979

SCHEMBL5888979

COc1cccc([C@@H](C)CBr)c1

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASR P41180 4/20 0.50
AOC3 Q16853 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
TAAR1 Q96RJ0 2/20 0.47
ABCB11 O95342 1/20 0.45
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5888983 1.00 CASR (0.50) CASRAOC3L3MBTL1TAAR1ABCB11
SCHEMBL11166044 0.86 CASR (0.48) CASRAOC3L3MBTL1TAAR1ABCB11
SCHEMBL10192231 0.83 CASR (0.51) CASRAOC3L3MBTL1TAAR1ABCB11
SCHEMBL11992976 0.83 CASR (0.51) CASRAOC3L3MBTL1TAAR1ABCB11
SCHEMBL14162717 0.83 CASR (0.51) CASRAOC3L3MBTL1TAAR1ABCB11
SCHEMBL2632814 0.83 CASR (0.51) CASRAOC3L3MBTL1TAAR1ABCB11
SCHEMBL4048471 0.82 PTGS1 (0.57) CASR
SCHEMBL11024645 0.82 HDAC4 (0.41) AOC3TAAR1
SCHEMBL24925773 0.81 ABCB11 (0.67) CASRAOC3L3MBTL1TAAR1ABCB11
SCHEMBL11224383 0.81 CASR (0.50) CASRAOC3L3MBTL1TAAR1ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7108896-B2 Method of increasing helical twisting power, optically active compound, liquid crystal compostion containing the same, and liquid crystal display device DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-09-19 US disclosed
US-20040021128-A1 Method of increasing helical twisting power, optically active compound, liquid crystal composition containing the same, and liquid crystal display device DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-02-05 US disclosed