Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889228 | 0.91 | KDR (0.44) | KDR | |
| SCHEMBL5889026 | 0.86 | KDR (0.44) | KDRKIT | |
| SCHEMBL5889007 | 0.78 | KDR (0.70) | KDRKIT | |
| SCHEMBL5889031 | 0.77 | KDR (0.44) | KDRKIT | |
| SCHEMBL5889117 | 0.71 | KDR (0.66) | KDRKIT | |
| SCHEMBL5888998 | 0.68 | KDR (0.70) | KDRKIT | |
| SCHEMBL5889115 | 0.67 | KDR (0.65) | KDR | |
| SCHEMBL5889233 | 0.66 | KDR (0.47) | KDR | |
| SCHEMBL7684972 | 0.64 | KDR (0.48) | KDRKIT | |
| SCHEMBL5889102 | 0.64 | KDR (0.66) | KDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115597-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2006-10-03 | — | — | US | disclosed |