SCHEMBL588923

SCHEMBL588923

NS(=O)(=O)c1cccc2c(O)cccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 1.00
LDHA P00338 1/20 0.77
CA2 P00918 5/20 0.61
CA1 P00915 3/20 0.61
CA9 Q16790 2/20 0.61
STAT3 P40763 1/20 0.52
FTO Q9C0B1 1/20 0.49
MCL1 Q07820 2/20 0.47
CYP2C9 P11712 2/20 0.47
HSD17B10 Q99714 1/20 0.47
ALPL P05186 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
DNMT1 P26358 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TTR P02766 1/20 0.47
MEN1 O00255 1/20 0.46
ESR1 P03372 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401806 1.00 CDK2 (1.00) CDK2LDHACA2CA1CA9
SCHEMBL9138970 0.89 CDK2 (0.78) CDK2LDHACA2CA1CA9
SCHEMBL1805457 0.87 LDHA (1.00) CDK2LDHACA2CA1CA9
SCHEMBL15851423 0.83 CDK2 (0.70) CDK2LDHACA2CA1CA9
SCHEMBL31399765 0.83 CDK2 (0.70) CDK2LDHAMCL1HSD17B10ALPL
SCHEMBL30165664 0.83 CDK2 (0.70) CDK2LDHAMCL1HSD17B10ALPL
SCHEMBL464971 0.83 CDK2 (0.70) CDK2LDHAMCL1HSD17B10ALPL
SCHEMBL899804 0.81 CDK2 (0.68) CDK2LDHACA2CA1CA9
SCHEMBL3165363 0.81 CDK2 (0.68) CDK2LDHACA2MCL1CYP2C9
SCHEMBL4676606 0.81 CDK2 (0.68) CDK2LDHAMCL1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US claimed
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US disclosed
US-20240034799-A1 METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS CEDARS SINAI MEDICAL CENTER (US) 2024-02-01 US disclosed
EP-4256086-A1 METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS Cedars-Sinai Medical Center (US) 2023-10-11 EP disclosed
US-20230279491-A1 TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS CEDARS-SINAI MEDICAL CENTER 2023-09-07 US disclosed
EP-4208021-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS Bio-Rad Laboratories, Inc. (US) 2023-07-12 EP disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
WO-2022119842-A1 METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS CEDARS-SINAI MEDICAL CENTER (US) 2022-06-09 WO disclosed
US-20220065878-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS BIO-RAD LABORATORIES, INC. 2022-03-03 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
EP-0260557-B1 ASYMMETRIC 1:2 METAL COMPLEX DYESTUFS BAYER AG (DE) 1991-11-27 EP disclosed
EP-0263356-B1 PROCESS FOR THE PREPARATION OF HYDROXYNAPHTHALENE SULFONIC AMIDES BAYER AG (DE) 1991-10-02 EP disclosed
US-4990523-A Treatment of chronic inflammatory joint disease with arylsulfonamides A. H. ROBINS COMPANY, INCORPORATED (US) 1991-02-05 US disclosed
WO-1990015600-A2 TREATMENT OF CHRONIC INFLAMMATORY JOINT DISEASE WITH ARYLSULFONAMIDES A.H. ROBINS COMPANY, INCORPORATED (US) 1990-12-27 WO disclosed
EP-0384893-A1 Process for the preparation of asymmetrical 1,2-metal complex dyestuffs CIBA-GEIGY AG (CH) 1990-08-29 EP disclosed
EP-0263356-A2 Process for the preparation of hydroxynaphthalene sulfonic amides BAYER AG (DE) 1988-04-13 EP disclosed
EP-0260557-A2 Asymmetric 1:2 metal complex dyestufs BAYER AG (DE) 1988-03-23 EP disclosed
US-4218566-A BRONCHODILATORS, ANTIINFLAMMATORY AGENTS AMERICAN CYANAMID COMPANY (US) 1980-08-19 US disclosed
US-3987067-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-10-19 US disclosed
US-3959319-A FREE FLOWING CRYSTALS THE UPJOHN COMPANY (US) 1976-05-25 US disclosed