SCHEMBL5889385

SCHEMBL5889385

CN1C(C)(C)CC(C(CC(=O)O)(C(=O)O)C2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
CYP2C19 P33261 2/20 0.33
NFKB1 P19838 1/20 0.33
CYP2D6 P10635 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317177 0.86 GAA (0.33) TSHRCYP2C19CYP2D6HIF1A
SCHEMBL11200071 0.84
SCHEMBL5649672 0.83 MEN1 (0.33) TSHRCYP2C19NFKB1
SCHEMBL7476142 0.82 CYP2D6 (0.33) TSHRCYP2C19CYP2D6HIF1A
SCHEMBL10581226 0.82
SCHEMBL11200066 0.81
SCHEMBL463019 0.81 CYP1A2 (0.31)
SCHEMBL9784297 0.80 TSHR (0.43) TSHRCYP2C19CYP2D6HIF1A
SCHEMBL8849430 0.80
SCHEMBL9497581 0.79 TSHR (0.30) TSHRCYP2C19NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP claimed
US-7105590-B2 Phenolfree stabilization of polyolefins CLARIANT FINANCE (BVI) LIMITED (VG) 2006-09-12 US disclosed
US-20040186207-A1 Phenolfree stabilization of polyolefins CLARIANT FINANCE (BVI) LIMITED (VG) 2004-09-23 US disclosed
EP-0856526-B1 OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME CHISSO CORP (JP) 2002-08-28 EP disclosed
US-6365652-B2 AMIDO OR CARBAMATE SUBSTITUTED TRISARYL-1,3,5-TRIAZINES USED AS ACTINIC RADIATION STABILIZER BY INCORPORATING THE ABOVE COMPOUND INTO THE ORGANIC POLYMER BY CHEMICAL BONDING CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-02 US disclosed
US-6313225-B2 High melt tension, high crystallization temperature; hollow moldings CHISSO CORPORATION (JP) 2001-11-06 US disclosed
US-20010037022-A1 Trisaryl-1,3,5-triazine ultraviolet light absorbers GUPTA RAM BABOO (US) 2001-11-01 US disclosed
US-6265576-B1 STABILIZERS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-24 US disclosed
US-20010004657-A1 OLEFIN(CO-) POLYMER COMPOSITIONS AND METHOD FOR PRODUCING THE SAME ANDCATALYST FOR OLEFIN (CO-) POLYMERIZATION AND METHOD FOR PRODUCING THE SAME CHISSO CORPORATION (JP) 2001-06-21 US disclosed
US-6231804-B1 USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER CHISSO CORPORATION (JP) 2001-05-15 US disclosed
US-4116933-A Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4101509-A Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions CIBA-GEIGY CORPORATION (US) 1978-07-18 US disclosed
US-4089842-A COLORFASTNESS, RADIATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1978-05-16 US disclosed
US-4087406-A Metal salts of hindered piperidine carboxylic acids and stabilized compositions CIBA-GEIGY CORPORATION (US) 1978-05-02 US disclosed
US-4069199-A Metal salts of hindered piperidine carboxylic acids and stabilized compositions CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed
US-4056507-A POLYMERS, ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-11-01 US disclosed
US-4031095-A Hindered piperidine carboxylic acids, metals salts thereof and stabilized compositions CIBA-GEIGY CORPORATION (US) 1977-06-21 US disclosed
US-4001181-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1977-01-04 US disclosed
US-3960809-A POLYMERS CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed
US-3939163-A Metal salts of hindered piperidine carboxylic acids and stabilized compositions CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037022-A1 Trisaryl-1,3,5-triazine ultraviolet light absorbers CRYZ, ERCC5, TELO2 TSHR 767/4885CYP2C19 976/4885NFKB1 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.