Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 6/20 | 0.60 |
| ▸ | CCND1 | P24385 | 6/20 | 0.60 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.60 |
| ▸ | CDK1 | P06493 | 4/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889698 | 1.00 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889922 | 0.91 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889923 | 0.91 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL7265006 | 0.87 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL7264998 | 0.87 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5890075 | 0.87 | CCNB2 (0.58) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889603 | 0.87 | CCNB2 (0.58) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889604 | 0.87 | CCNB2 (0.58) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5890080 | 0.87 | CCNB2 (0.58) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889707 | 0.83 | CCNB2 (0.73) | CDK4CCND1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115296-B2 | N-alkylaspartyl amide derivative and sweetening agent | AJINOMOTO CO., INC. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20040071851-A1 | Novel N-alkylaspartyl amide derivative and sweetening agent | AJINOMOTO CO. INC (JP) | 2004-04-15 | — | — | US | disclosed |