Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.60 |
| ▸ | CCND1 | P24385 | 4/20 | 0.60 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.60 |
| ▸ | CDK1 | P06493 | 3/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265006 | 1.00 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL6735911 | 0.89 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL6735912 | 0.89 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889698 | 0.87 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889696 | 0.87 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL7086040 | 0.87 | CCNB2 (0.65) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL187352 | 0.85 | MAOA (0.56) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5702556 | 0.85 | APP (0.65) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL4623825 | 0.85 | PDCD1 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL4623828 | 0.85 | PDCD1 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548096-B1 | Aspartyl dipeptide ester derivatives and sweeteners | AJINOMOTO CO., INC. (JP) | 2003-04-15 | — | — | US | disclosed |
| EP-1070726-A1 | ASPARTYL DIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-01-24 | — | — | EP | disclosed |