Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL128284 | 1.00 | — | — | |
| Dimethylamine SCHEMBL28101991 | 0.97 | CA2 (0.39) | CA2TSHRUSP2CA1TDP1 | |
| Dimethylamine SCHEMBL27559355 | 0.91 | CA2 (0.35) | CA2TSHRUSP2CA1TDP1 | |
| Dimethylamine SCHEMBL27559356 | 0.91 | CA2 (0.35) | CA2TSHRUSP2CA1TDP1 | |
| SCHEMBL2773032 | 0.89 | TSHR (0.53) | CA2TSHRUSP2CA1TDP1 | |
| SCHEMBL27259142 | 0.89 | TSHR (0.50) | CA2TSHRUSP2CA1TDP1 | |
| SCHEMBL27308161 | 0.89 | TSHR (0.50) | CA2TSHRUSP2CA1TDP1 | |
| SCHEMBL5991 | 0.89 | — | — | |
| SCHEMBL27346657 | 0.89 | TSHR (0.50) | CA2TSHRUSP2CA1TDP1 | |
| Ethane SCHEMBL4847941 | 0.87 | CA2 (0.37) | CA2TSHRUSP2CA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105580-A1 | Polymers For Oilfield Applications | BJ SERVICES COMPANY (US) | 2010-04-29 | — | — | US | claimed |
| US-8114819-B2 | Polymers for oilfield applications | BAKER HUGHES INCORPORATED (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100105580-A1 | Polymers For Oilfield Applications | BJ SERVICES COMPANY (US) | 2010-04-29 | — | — | US | disclosed |