Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588137 | 0.98 | TSHR (0.48) | TSHRSLC22A6ABCC4MAPTLMNA | |
| SCHEMBL588848 | 0.96 | TSHR (0.47) | TSHRSLC22A6ABCC4MAPTLMNA | |
| SCHEMBL588940 | 0.96 | TSHR (0.47) | TSHRSLC22A6ABCC4MAPTLMNA | |
| SCHEMBL588709 | 0.96 | TSHR (0.47) | TSHRSLC22A6ABCC4MAPTLMNA | |
| SCHEMBL3293977 | 0.94 | ABCC4 (0.47) | TSHRSLC22A6ABCC4MAPTLMNA | |
| SCHEMBL3347194 | 0.92 | ABCC4 (0.50) | TSHRSLC22A6ABCC4MAPTLMNA | |
| SCHEMBL28190024 | 0.90 | ABCC4 (0.48) | TSHRSLC22A6ABCC4MAPTLMNA | |
| SCHEMBL588136 | 0.89 | TSHR (0.44) | TSHRMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL181453 | 0.85 | LMNA (0.41) | TSHRABCC4MAPTLMNAALDH1A1 | |
| SCHEMBL28495861 | 0.85 | TSHR (0.44) | TSHRABCC4MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114819-B2 | Polymers for oilfield applications | BAKER HUGHES INCORPORATED (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100105580-A1 | Polymers For Oilfield Applications | BJ SERVICES COMPANY (US) | 2010-04-29 | — | — | US | disclosed |