SCHEMBL589031

SCHEMBL589031

Nc1ccn([C@@H]2O[C@H](COP(=O)(O)OC3(C(=O)O)CC(O)[C@@H](NC(=O)CNC(=O)CCSSc4ccccn4)[C@H](C(O)[C@H](O)CO)O3)[C@@H](O)[C@H]2O)c(=O)n1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ST6GAL1 P15907 9/20 0.41
P2RY2 P41231 3/20 0.38
P2RY6 Q15077 3/20 0.38
CD22 P20273 3/20 0.38
P2RY4 P51582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13153381 1.00 ST6GAL1 (0.41) ST6GAL1P2RY2P2RY6CD22P2RY4
SCHEMBL2602690 0.96 ST6GAL1 (0.40) ST6GAL1P2RY2P2RY6CD22P2RY4
SCHEMBL18084277 0.96 ST6GAL1 (0.39) ST6GAL1P2RY2P2RY6CD22
SCHEMBL600526 0.90 ST6GAL1 (0.44) ST6GAL1
SCHEMBL16645359 0.88 ST6GAL1 (0.44) ST6GAL1P2RY2P2RY6CD22P2RY4
SCHEMBL17000271 0.87 ST6GAL1 (0.43) ST6GAL1P2RY2P2RY6CD22P2RY4
SCHEMBL18713167 0.87 ST6GAL1 (0.43) ST6GAL1P2RY2P2RY6CD22P2RY4
SCHEMBL18713166 0.87 ST6GAL1 (0.43) ST6GAL1P2RY2P2RY6CD22P2RY4
SCHEMBL10187590 0.86 ST6GAL1 (0.45) ST6GAL1P2RY2P2RY6CD22P2RY4
SCHEMBL20832018 0.86 CD22 (0.43) ST6GAL1P2RY2P2RY6CD22P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160251409-A1 Targeted Delivery of Factor VIII Proteins to Platelets NOVO NORDISK AS (DK) 2016-09-01 US disclosed
EP-2417155-B1 TARGETED DELIVERY OF FACTOR VIII PROTEINS TO PLATELETS NOVO NORDISK AS (DK) 2013-06-19 EP disclosed
EP-2417155-B1 TARGETED DELIVERY OF FACTOR VIII PROTEINS TO PLATELETS NOVO NORDISK AS (DK) 2013-06-19 EP disclosed
EP-2417155-A1 TARGETED DELIVERY OF FACTOR VIII PROTEINS TO PLATELETS Novo Nordisk A/S (DK) 2012-02-15 EP disclosed
WO-2010115866-A1 TARGETED DELIVERY OF FACTOR VIII PROTEINS TO PLATELETS NOVO NORDISK A/S (DK) 2010-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160251409-A1 Targeted Delivery of Factor VIII Proteins to Platelets F13B, F8, F13A1 ST6GAL1 2265/4885P2RY2 3692/4885P2RY6 2807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.