SCHEMBL5890798

SCHEMBL5890798

CCCCC1=Cc2c(-c3ccccc3-c3cccc4ccccc34)cccc2C1[Hf](C1C(CCCC)=Cc2c(-c3ccccc3-c3cccc4ccccc34)cccc21)[SiH](C)C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.34
ALOX15 P16050 2/20 0.33
CNR2 P34972 1/20 0.33
HTR7 P34969 1/20 0.32
TLR8 Q9NR97 1/20 0.31
DRD2 P14416 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5890083 0.93 HTR7 (0.33) CNR1ALOX15HTR7DRD2SLC6A4
SCHEMBL20815319 0.87 HTR7 (0.33) ALOX15HTR7DRD2SLC6A4
SCHEMBL5890112 0.85 BCHE (0.31)
SCHEMBL5890425 0.85 BCHE (0.31)
SCHEMBL5890880 0.84 BCHE (0.30)
SCHEMBL5890006 0.84 BCHE (0.30)
SCHEMBL5890385 0.83 NPC1 (0.32)
SCHEMBL5890176 0.82
SCHEMBL5890796 0.82
SCHEMBL5890944 0.82 BCHE (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122498-B2 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-10-17 US disclosed