⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131951 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL27883863 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL4088567 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL9244 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL473400 | 0.86 | — | — | |
| Sulfuric Acid SCHEMBL11647815 | 0.82 | MAPT (0.43) | — | |
| SCHEMBL8997845 | 0.80 | TSHR (0.50) | — | |
| Mechlorethamine SCHEMBL12802922 | 0.79 | MAPT (0.86) | — | |
| Hydrochloric Acid SCHEMBL8950161 | 0.78 | TSHR (0.50) | — | |
| Acrylic Acid SCHEMBL19371529 | 0.74 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129361-B2 | Thienylazolylalkoxyethanamines, their preparation and their application as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-10-31 | — | — | US | disclosed |
| EP-1072266-B1 | THIENYLAZOLYLALCOXYETHANAMINES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2005-08-24 | — | — | EP | disclosed |
| US-20040162324-A1 | Thienylazolylalkoxyethanamines, their preparation and their application as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. | 2004-08-19 | — | — | US | disclosed |
| US-20020188017-A1 | Thienylazolylalkoxyethanamines, their preparation and their application as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. | 2002-12-12 | — | — | US | disclosed |
| EP-1029852-B1 | PROCESS FOR OBTAINING ENANTIOMERS OF CIS-OLIRTINE | ESTEVE LABOR DR (ES) | 2002-11-06 | — | — | EP | disclosed |
| US-6410582-B1 | ANALGESICS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-06-25 | — | — | US | disclosed |
| EP-1072266-A1 | THIENYLAZOLYLALCOXYETHANAMINES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2001-01-31 | — | — | EP | disclosed |
| US-6118009-A | Process for obtaining enantiomers of cis-olirtine | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-09-12 | — | — | US | disclosed |
| EP-1029852-A1 | PROCESS FOR OBTAINING ENANTIOMERS OF CIS-OLIRTINE | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-08-23 | — | — | EP | disclosed |
| US-4507499-A | N-(4-Hydroxybenzyl)-3,4,5-trimethoxybenzamide and method for producing trimethobenzamide chlorohydrate | FRANCIS S.P.A. (IT) | 1985-03-26 | — | — | US | disclosed |
| US-4268439-A | Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |