Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 8/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5897283 | 0.93 | ITGB1 (0.53) | ITGB1ITGA4MAPTRAB9ANPC1 | |
| SCHEMBL5896625 | 0.89 | ITGB1 (0.58) | ITGB1ITGA4MAPTRAB9ANPC1 | |
| SCHEMBL5896454 | 0.85 | ITGB1 (0.53) | ITGB1ITGA4MAPTRAB9ANPC1 | |
| SCHEMBL5865240 | 0.82 | ITGB1 (0.58) | ITGB1ITGA4MAPTRAB9ANPC1 | |
| SCHEMBL5897280 | 0.79 | ITGB1 (0.53) | ITGB1ITGA4MAPTMEN1KMT2A | |
| SCHEMBL6343898 | 0.78 | ITGB1 (0.63) | ITGB1ITGA4MAPTRAB9ANPC1 | |
| SCHEMBL5896446 | 0.78 | MAPT (0.61) | ITGB1ITGA4MAPTRAB9ANPC1 | |
| SCHEMBL6346579 | 0.78 | ITGB1 (0.55) | ITGB1ITGA4MAPTRAB9ANPC1 | |
| SCHEMBL6345157 | 0.78 | ITGB1 (0.63) | ITGB1ITGA4MAPTRAB9ANPC1 | |
| SCHEMBL6344042 | 0.78 | ITGB1 (0.67) | ITGB1ITGA4SMN1; SMN2ITGB7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091242-B2 | Beta-amino acid derivatives as integrin receptor antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-15 | — | — | US | disclosed |
| US-20040058904-A1 | Beta-amino acid derivatives as integrin receptor antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | US | disclosed |
| EP-1326828-A1 | BETA-AMINO ACID DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002030875-A1 | BETA-AMINO ACID DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058904-A1 | Beta-amino acid derivatives as integrin receptor antagonists | ITGAL, ITGB1, ITGB2 | ITGB1 2/4885ITGA4 15/4885MAPT 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.