Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 8/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896459 | 0.93 | ITGB1 (0.53) | ITGB1ITGA4MAPTNPC1RAB9A | |
| SCHEMBL5865240 | 0.90 | ITGB1 (0.58) | ITGB1ITGA4MAPTNPC1RAB9A | |
| SCHEMBL5897280 | 0.86 | ITGB1 (0.53) | ITGB1ITGA4MAPTNAMPTITGB7 | |
| SCHEMBL5896625 | 0.82 | ITGB1 (0.58) | ITGB1ITGA4MAPTNPC1RAB9A | |
| SCHEMBL6353998 | 0.80 | ITGB1 (0.61) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5896454 | 0.79 | ITGB1 (0.53) | ITGB1ITGA4MAPTNPC1RAB9A | |
| SCHEMBL6344233 | 0.78 | ITGB1 (0.59) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5700782 | 0.75 | ITGB1 (0.65) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5897049 | 0.74 | POLB (0.54) | MAPTKMT2A | |
| SCHEMBL5896878 | 0.73 | MAPT (0.47) | MAPTNPC1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091242-B2 | Beta-amino acid derivatives as integrin receptor antagonists | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-15 | — | — | US | disclosed |