SCHEMBL5897178

SCHEMBL5897178

CCCC(CCC(C)O)C(=NO)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.35
AOC3 Q16853 2/20 0.34
MAPT P10636 2/20 0.34
USP2 O75604 1/20 0.34
HPGD P15428 1/20 0.34
XBP1 P17861 1/20 0.34
RAB9A P51151 3/20 0.33
ATM Q13315 2/20 0.33
NPC1 O15118 2/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ABCB1 P08183 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5360512 0.91 PRSS1 (0.36) POLBMAPTUSP2HPGDXBP1
SCHEMBL5897747 0.89 SMN1; SMN2 (0.38) POLBMAPTUSP2HPGDXBP1
SCHEMBL2284727 0.88 CSNK1E (0.40) ALDH1A1HDAC3HDAC4HDAC1HDAC2
SCHEMBL7086708 0.80 PTGS2 (0.41) POLBMAPTATMMAPK1MEN1
SCHEMBL31657719 0.76 CSNK1E (0.39) USP2RAB9ANPC1HTTMEN1
SCHEMBL5706492 0.75 POLB (0.37) POLBAOC3MAPTUSP2HPGD
SCHEMBL10781135 0.75 PRSS1 (0.36) POLBMAPTUSP2HPGDXBP1
SCHEMBL5706428 0.73 MEN1 (0.37) POLBAOC3MAPTUSP2HPGD
SCHEMBL4218257 0.73 ATM (0.39) POLBAOC3MAPTHPGDXBP1
SCHEMBL5918159 0.72 MEN1 (0.42) POLBMAPTUSP2HPGDXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5993757-A Reoximation of metal extraction circuit organics HENKEL CORPORATION (US) 1999-11-30 US claimed
WO-1998039492-A1 REOXIMATION OF METAL EXTRACTION CIRCUIT ORGANICS HENKEL CORPORATION (US) 1998-09-11 WO claimed
WO-1998017363-A1 CONCENTRATED SOLUTIONS OF OXIME METAL EXTRACTANTS AND METHOD OF FORMULATING EXTRACTANT COMPOSITIONS THEREFROM HENKEL CORPORATION (US) 1998-04-30 WO claimed
EP-0085522-B1 SOLVENT EXTRACTION HENKEL CORPORATION (a Delaware corp.) (US) 1989-04-26 EP claimed
US-4544532-A HYDROXY ARYL KETOXIMES AND HYDROXY ARYL ALDOXIMES HENKEL CORPORATION (US) 1985-10-01 US claimed
US-4507268-A EXTRACTION OF COPPER WITH HYDROXYARYLKETOXIMES AND ALDOXIMES HENKEL CORPORATION (US) 1985-03-26 US claimed
EP-0085522-A2 Solvent extraction HENKEL CORPORATION (a Delaware corp.) (US) 1983-08-10 EP claimed
US-7025899-B2 Concentrated solutions of oxime metal extractants and method of formulating extractant compositions therefrom COGNIS CORPORATION (US) 2006-04-11 US disclosed
US-6702872-B1 Processes for the recovery of copper from aqueous solutions containing nitrate ions COGNIS CORPORATION 2004-03-09 US disclosed
US-6599414-B1 When the aqueous phase used in the wash stage is first contacted with copper metal, significant increase in removal of iron ions from loaded organic solvent solution is obtained, i.e. iron scrubbing efficiency is significantly improved COGNIS CORPORATION 2003-07-29 US disclosed
US-6596053-B2 Oxime extractant in a water immiscible organic solvent COGNIS CORPORATION 2003-07-22 US disclosed
US-20030061910-A1 Processes for the recovery of copper from aqueous solutions containing nitrate ions COGNIS IP MANAGEMENT GMBH (DE) 2003-04-03 US disclosed
WO-2003014422-A1 IMPROVEMENTS IN SOLVENT EXTRACTION PROCESSES FOR METAL RECOVERY COGNIS CORPORATION (US) 2003-02-20 WO disclosed
US-5470552-A Nickel extraction process HENKEL CORPORATION (US) 1995-11-28 US disclosed
US-4957714-A RECOVERING COPPER FROM HYDROXY OXIME EXTRACTANT HENKEL CORPORATION (US) 1990-09-18 US disclosed
EP-0085522-B1 SOLVENT EXTRACTION HENKEL CORPORATION (a Delaware corp.) (US) 1989-04-26 EP disclosed
US-4582689-A COMPLEXING IRON AND COOPER SALTS, COUNTERCURRENT FLOW AND VARYING RESIDENCE TIMES HENKEL CORPORATION (US) 1986-04-15 US disclosed
US-4544532-A HYDROXY ARYL KETOXIMES AND HYDROXY ARYL ALDOXIMES HENKEL CORPORATION (US) 1985-10-01 US disclosed
US-4507268-A EXTRACTION OF COPPER WITH HYDROXYARYLKETOXIMES AND ALDOXIMES HENKEL CORPORATION (US) 1985-03-26 US disclosed
EP-0085522-A2 Solvent extraction HENKEL CORPORATION (a Delaware corp.) (US) 1983-08-10 EP disclosed