SCHEMBL5898100

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16975161	0.86	CA2 (0.40)	CA2MAPK1CA1CHRM1AKR1A1
	SCHEMBL8927877	0.86	CA2 (0.54)	CA2MAPK1CA1TDP1TSHR
	SCHEMBL1983515	0.86	CA2 (0.54)	CA2MAPK1CA1TDP1CYP3A4
	SCHEMBL7765839	0.85	CHRM1 (0.42)	CA2MAPK1CA1CHRM1AKR1A1
	SCHEMBL5483393	0.83	CA2 (0.42)	CA2TSHRALDH1A1
	SCHEMBL10583487	0.83	CA2 (0.42)	CA2MAPK1CA1
	SCHEMBL10456170	0.81	CHRM1 (0.39)	CA2MAPK1CA1CHRM1AKR1A1
	SCHEMBL16098245	0.81	CA2 (0.43)	CA2MAPK1CA1ALDH1A1CES2
	SCHEMBL7904735	0.81	CA2 (0.43)	CA2MAPK1CA1CHRM1AKR1A1
	SCHEMBL10535669	0.80	CA2 (0.39)	CA2MAPK1CA1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.