SCHEMBL5898904

SCHEMBL5898904

C=C(CC=C(C)C(=O)O)C(=O)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
HCAR2 Q8TDS4 2/20 0.43
NAAA Q02083 1/20 0.41
RAD52 P43351 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
EPHX1 P07099 1/20 0.39
FAAH O00519 2/20 0.39
LMNA P02545 3/20 0.37
HTT P42858 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CES2 O00748 1/20 0.37
HPGD P15428 1/20 0.37
EP300 Q09472 1/20 0.37
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438580 1.00 TSHR (0.57) TSHRHCAR2NAAARAD52NPSR1
SCHEMBL8961812 1.00 TSHR (0.57) TSHRHCAR2NAAARAD52NPSR1
SCHEMBL3670738 0.94 TSHR (0.47) TSHRHCAR2NAAARAD52NPSR1
SCHEMBL11352555 0.92 TSHR (0.56) TSHRHCAR2NAAARAD52NPSR1
SCHEMBL11335009 0.92 TSHR (0.56) TSHRHCAR2NAAARAD52NPSR1
SCHEMBL11236476 0.91 TSHR (0.58) TSHRHCAR2NAAARAD52NPSR1
SCHEMBL10477468 0.91 TSHR (0.54) TSHRHCAR2NAAARAD52NPSR1
SCHEMBL8425837 0.90 TSHR (0.55) TSHRHCAR2NAAANPSR1HTT
SCHEMBL8430254 0.90 TSHR (0.55) TSHRHCAR2NAAANPSR1HTT
Butadiene SCHEMBL8956976 0.90 TSHR (0.44) TSHRHCAR2NAAANPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7084205-B2 Polymeric compositions for dewatering sewage sludges CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2006-08-01 US disclosed
EP-1311614-B1 POLYMERIC COMPOSITIONS FOR DEWATERING SEWAGE SLUDGES CIBA SPEC CHEM WATER TREAT LTD (GB) 2005-06-08 EP disclosed
US-20030178371-A1 Polymeric compositions for dewatering sewage sludges CIBA SPECIALTY CHEMICALS WATER TREATMENT LIMITED (GB) 2003-09-25 US disclosed
EP-1311614-A1 POLYMERIC COMPOSITIONS FOR DEWATERING SEWAGE SLUDGES Ciba Specialty Chemicals Water Treatments Limited (GB) 2003-05-21 EP disclosed
WO-2002016495-A1 POLYMERIC COMPOSITIONS FOR DEWATERING SEWAGE SLUDGES CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2002-02-28 WO disclosed
EP-0150933-B2 A process for the production of polymers and aqueous solutions thereof ALLIED COLLOIDS LTD (GB) 1997-08-20 EP disclosed
US-4873166-A Liquid developer for electrophotography MITSUBISHI PAPER MILLS, LTD. (JP) 1989-10-10 US disclosed
EP-0150933-B1 A PROCESS FOR THE PRODUCTION OF POLYMERS AND AQUEOUS SOLUTIONS THEREOF Ciba Specialty Chemicals Water Treatments Limited (GB) 1989-07-26 EP disclosed
EP-0126528-B1 POLYMER DISPERSIONS AND THEIR PREPARATION Ciba Specialty Chemicals Water Treatments Limited (GB) 1988-11-30 EP disclosed
EP-0233014-A2 Polymers and processes for their production from water soluble monomers Ciba Specialty Chemicals Water Treatments Limited (GB) 1987-08-19 EP disclosed
US-4599379-A Process for the production of polymers and aqueous solutions thereof ALLIED COLLOIDS LTD. (GB) 1986-07-08 US disclosed
EP-0150933-A2 A process for the production of polymers and aqueous solutions thereof Ciba Specialty Chemicals Water Treatments Limited (GB) 1985-08-07 EP disclosed
US-4528321-A Polymer dispersions and their preparation ALLIED COLLOIDS LIMITED (GB) 1985-07-09 US disclosed
EP-0126528-A2 Polymer dispersions and their preparation Ciba Specialty Chemicals Water Treatments Limited (GB) 1984-11-28 EP disclosed