Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438580 | 1.00 | TSHR (0.57) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL5898904 | 1.00 | TSHR (0.57) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL3670738 | 0.94 | TSHR (0.47) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL11352555 | 0.92 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL11335009 | 0.92 | TSHR (0.56) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL11236476 | 0.91 | TSHR (0.58) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL10477468 | 0.91 | TSHR (0.54) | TSHRHCAR2NAAARAD52NPSR1 | |
| SCHEMBL8425837 | 0.90 | TSHR (0.55) | TSHRHCAR2NAAANPSR1HTT | |
| SCHEMBL8430254 | 0.90 | TSHR (0.55) | TSHRHCAR2NAAANPSR1HTT | |
| Butadiene SCHEMBL8956976 | 0.90 | TSHR (0.44) | TSHRHCAR2NAAANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530532-A | Image forming apparatus using intermediate transfer member having surface roughness to toner size ratio | MINOLTA CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| US-4367745-A | Conformable electrically conductive compositions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-01-11 | — | — | US | disclosed |
| US-4273135-A | IMPROVED ELECTROCONDUCTIVE INTERFACE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-06-16 | — | — | US | disclosed |