Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372326 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL1011863 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL11181373 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL152343 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL30417411 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL153538 | 1.00 | POLA1 (0.31) | POLA1 | |
| SCHEMBL155172 | 0.93 | — | — | |
| SCHEMBL30174149 | 0.93 | — | — | |
| Bromide SCHEMBL31070248 | 0.91 | — | — | |
| SCHEMBL7793895 | 0.91 | FAAH (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105617-B2 | Metal 8-hydroxyquinoline-functionalized polymers and related materials and methods of making and using the same | GEORGIA TECH RESEARCH CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |
| US-20050131175-A1 | Metal 8-hydroxyquinoline-functionalized polymers and related materials and methods of making and using the same | GEORGIA TECH RESEARCH CORPORATION | 2005-06-16 | — | — | US | disclosed |
| US-4033982-A | REACTING NORBORNENES WITH SULFUR | GENERAL ELECTRIC COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131175-A1 | Metal 8-hydroxyquinoline-functionalized polymers and related materials and methods of making and using the same | KCNQ2, KCNQ3, KCNQ1 | POLA1 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.