Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 14/20 | 0.46 |
| ▸ | TEK | Q02763 | 10/20 | 0.46 |
| ▸ | BRAF | P15056 | 4/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899288 | 0.90 | KDR (0.47) | CA12CA1CA2CA9KDR | |
| SCHEMBL5899283 | 0.89 | BRAF (0.44) | KDRTEKBRAFPDGFRB | |
| SCHEMBL5899284 | 0.88 | KDR (0.44) | CA12CA1CA2CA9KDR | |
| SCHEMBL5899271 | 0.82 | CDK8 (0.49) | CA1CA2CA9KDRBRAF | |
| SCHEMBL5899310 | 0.77 | KDR (0.51) | KDRTEKBRAFPDGFRBRAF1 | |
| SCHEMBL5899255 | 0.70 | BRAF (0.56) | KDRTEKBRAFRAF1 | |
| SCHEMBL937617 | 0.70 | KDR (0.69) | CA12CA1CA2CA9KDR | |
| SCHEMBL21750852 | 0.69 | CA12 (0.70) | CA12CA1CA2CA9KDR | |
| SCHEMBL4340395 | 0.68 | CA12 (0.69) | CA12CA1CA2CA9KDR | |
| SCHEMBL13541769 | 0.68 | CA12 (0.69) | CA12CA1CA2CA9KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241301-A1 | Urea derivatives and their use as tyrosinkinase inhibitors | MERCK PATENT GMBH (DE) | 2006-10-26 | — | — | US | claimed |
| US-20060241301-A1 | Urea derivatives and their use as tyrosinkinase inhibitors | MERCK PATENT GMBH (DE) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241301-A1 | Urea derivatives and their use as tyrosinkinase inhibitors | TIE1, UCK2, UTS2R | CA12 3994/4885CA1 4600/4885CA2 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.