SCHEMBL5899539

SCHEMBL5899539

CC1(C)OB(C(=C(c2ccccc2)c2ccccc2)c2ccccc2)OC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.39
LIPG Q9Y5X9 2/20 0.39
P4HB P07237 1/20 0.38
ANPEP P15144 1/20 0.35
LAP3 P28838 1/20 0.35
ESR1 P03372 3/20 0.33
APLNR P35414 1/20 0.33
PTGS2 P35354 2/20 0.32
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
CYP19A1 P11511 3/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6235492 0.92 ESR1 (0.47) LPLLIPGESR1PTGS2CYP19A1
SCHEMBL6235485 0.92 ESR1 (0.47) LPLLIPGESR1PTGS2CYP19A1
SCHEMBL6236173 0.90 LPL (0.42) LPLLIPGP4HBANPEPLAP3
SCHEMBL6236165 0.90 LPL (0.42) LPLLIPGP4HBANPEPLAP3
SCHEMBL6236171 0.90 LPL (0.42) LPLLIPGP4HBANPEPLAP3
SCHEMBL6236396 0.80 ATM (0.36) LPLLIPGP4HBANPEPLAP3
SCHEMBL6236403 0.80 ATM (0.36) LPLLIPGP4HBANPEPLAP3
SCHEMBL6236400 0.80 ATM (0.36) LPLLIPGP4HBANPEPLAP3
SCHEMBL6232862 0.79 ATM (0.35) LPLLIPGP4HBANPEPLAP3
SCHEMBL6232861 0.79 ATM (0.35) LPLLIPGP4HBANPEPLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993463-B1 ALKENE BORATES AND A PROCESS FOR COVALENTLY COUPLING ORGANIC COMPOUNDS BORON MOLECULAR PTY LTD (AU) 2005-11-30 EP claimed
US-20030114638-A1 Alkene borates and a process for covalently coupling organic compounds COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-06-19 US claimed
EP-0993463-A4 ALKENE BORATES AND A PROCESS FOR COVALENTLY COUPLING ORGANIC COMPOUNDS COMMW SCIENT IND RES ORG (AU) 2002-06-12 EP claimed
US-20020016489-A1 Alkene borates and a process for covalently coupling organic compounds COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION 2002-02-07 US claimed
US-6288259-B1 1,3,2-DIOXABOROLANES OR OR DIOXABOROLANES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2001-09-11 US claimed
EP-0993463-A1 ALKENE BORATES AND A PROCESS FOR COVALENTLY COUPLING ORGANIC COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-04-19 EP claimed
WO-1998058935-A1 ALKENE BORATES AND A PROCESS FOR COVALENTLY COUPLING ORGANIC COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1998-12-30 WO claimed
US-9328097-B2 Thermally activated delayed fluorescence material, a method of synthesizing the same and an OLED device using the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-05-03 US disclosed
US-9328097-B2 Thermally activated delayed fluorescence material, a method of synthesizing the same and an OLED device using the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-05-03 US disclosed
CN-102850177-B Application of bistriphenylene derivative in organic electroluminescent component ZHENG JIANHONG (CN) 2015-12-16 CN disclosed
US-20150280138-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, A METHOD OF SYNTHESIZING THE SAME AND AN OLED DEVICE USING THE SAME SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2015-10-01 US disclosed
US-20150280138-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, A METHOD OF SYNTHESIZING THE SAME AND AN OLED DEVICE USING THE SAME SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2015-10-01 US disclosed
US-8974920-B2 Application of triphenylene derivatives in organic electroluminescent devices NATIONAL TSING HUA UNIVERSITY (TW) 2015-03-10 US disclosed
EP-1127060-B1 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2004-04-07 EP disclosed
US-6680401-B1 BORON COMPOUNDS SUCH AS 4-(METHOXYMETHYL)-1,3,2-DIOXABOROLANE, USED AS COUPLERS OR CHEMICAL INTERMEDIATES FOR DRUGS, PESTICIDES OR IN COMBINATORIAL CHEMISTRY COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-01-20 US disclosed
US-20030114638-A1 Alkene borates and a process for covalently coupling organic compounds COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-06-19 US disclosed
US-6506925-B2 Synthesis from haloalkenes or pseudo-haloalkenes COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-01-14 US disclosed
EP-1127060-A4 HYDROBORONATION PROCESS COMMW SCIENT IND RES ORG (AU) 2002-08-21 EP disclosed
EP-1127060-A1 HYDROBORONATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2001-08-29 EP disclosed
WO-2000027853-A1 HYDROBORONATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016489-A1 Alkene borates and a process for covalently coupling organic compounds ALK, ORC3, ALKBH3 LPL 4318/4885LIPG 4370/4885P4HB 716/4885
US-20030114638-A1 Alkene borates and a process for covalently coupling organic compounds ALK, ORC3, ALKBH3 LPL 4318/4885LIPG 4370/4885P4HB 716/4885
US-20150280138-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, A METHOD OF SYNTHESIZING THE SAME AND AN OLED DEVICE USING THE SAME OCIAD1, OCIAD2, NOM1 LPL 1415/4885LIPG 3279/4885P4HB 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.