Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894940 | 0.89 | CTSS (0.46) | CTSSCTSL | |
| SCHEMBL3903777 | 0.85 | CTSS (0.44) | CTSSCTSL | |
| SCHEMBL3893518 | 0.84 | CTSS (0.43) | CTSSCTSLCTSBCTSK | |
| SCHEMBL3895393 | 0.84 | CTSS (0.46) | CTSSCTSL | |
| SCHEMBL3906122 | 0.84 | CTSS (0.48) | CTSSCTSLCTSBCTSK | |
| SCHEMBL5899670 | 0.83 | CTSS (0.46) | CTSSCTSL | |
| SCHEMBL3897669 | 0.82 | CTSS (0.47) | CTSSCTSL | |
| SCHEMBL3907679 | 0.81 | CTSS (0.48) | CTSSCTSL | |
| SCHEMBL3907688 | 0.79 | CTSS (0.49) | CTSSCTSL | |
| SCHEMBL3906505 | 0.79 | CTSS (0.46) | CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982263-B2 | Nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | claimed |