Methylene Chloride

Methylene Chloride

SCHEMBL58997

CC(C)OC(C)C.ClCCl

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL7521557 0.93 MAPK1 (0.42) MAPK1ALDH1A1TSHR
Cyclohexane SCHEMBL4991233 0.89 MAPK1 (0.40) MAPK1ALDH1A1TSHR
Ethyl Chloride SCHEMBL10588167 0.88 MAPK1 (0.44) MAPK1ALDH1A1TSHR
Hexane SCHEMBL9455882 0.84 TSHR (0.43) MAPK1ALDH1A1TSHR
Acetone SCHEMBL11413386 0.84 TSHR (0.41) MAPK1ALDH1A1TSHR
Ether SCHEMBL15135184 0.84 MAPK1 (0.36) MAPK1
Chloromethane SCHEMBL11103401 0.82
SCHEMBL7240952 0.82
SCHEMBL1296 0.82
SCHEMBL10940023 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160246-A Process for recovering valsartan from valsartan mother liquor 江苏新瑞药业有限公司 2022-10-11 CN claimed
CN-106905398-B Synthetic method of sofosbuvir ZHEJIANG A & F UNIVERSITY (CN) 2019-12-10 CN claimed
CN-106905398-A A kind of synthetic method of Suo Feibuwei 浙江农林大学 2017-06-30 CN claimed
CN-102399253-B A kind of preparation method of Tan Bolong acetic ester BEIJING KEYIFENG BIOTECH DEVELOPMENT CO., LTD. (CN) 2015-12-09 CN claimed
CN-102351881-B Stable levofloxacin hydrochloride compound TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD 2014-04-09 CN claimed
CN-103242356-A Preparation method of bortezomib intermediate isobutaneboronic acid SUZHOU HEALTH COLLEGE 2013-08-14 CN claimed
CN-102229601-B Hexahydro-1-(5-isoquinoline sulfonyl)-1 (H)-1, 4- diazepine hydrochloride amorphous compound TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD 2013-07-03 CN claimed
CN-102399253-A Preparation method of trenbolone acetate BEIJING KEYIFENG BIOTECH DEV CO LTD 2012-04-04 CN claimed
CN-102351881-A Stable levofloxacin hydrochloride compound TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD 2012-02-15 CN claimed
CN-102010381-B Improved preparation method of valsartan SHANDONG NEW TIME PHARMACEUTICAL Co.,Ltd. (CN) 2012-02-08 CN claimed
CN-102229601-A Hexahydro-1-(5-isoquinoline sulfonyl)-1 (H)-1, 4- diazepine hydrochloride amorphous compound TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD 2011-11-02 CN claimed
CN-102010381-A Improved preparation method of valsartan SHANDONG XINSHIDAI PHARMACEUTICAL CO LTD 2011-04-13 CN claimed
US-20090286989-A1 Process for High Purity Anastrozole SHILPA MEDICARE LTD. (IN) 2009-11-19 US claimed
EP-1994014-A1 IMPROVED PROCESS FOR HIGH PURITY ANASTROZOLE Shilpa Medicare Limited (IN) 2008-11-26 EP claimed
WO-2007105231-A1 IMPROVED PROCESS FOR HIGH PURITY ANASTROZOLE SHILPA MEDICARE LTD. (IN) 2007-09-20 WO claimed
US-6433164-B1 None US disclosed
CN-117999257-A Bicyclic heterocyclic derivatives having virus proliferation inhibitory activity and pharmaceutical compositions containing the same 盐野义制药株式会社 2024-05-07 CN disclosed
US-3944541-A 22-Cyano-24-norcholanes AMERICAN HOME PRODUCTS CORPORATION (US) 1976-03-16 US disclosed
US-3944577-A Novel pregnane-21-oic acid derivatives SCHERING AKTIENGESELLSCHAFT (DT) 1976-03-16 US disclosed
US-3932388-A STEROIDS, GLUCOCORTICOID ACITIVITY SCHERING CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286989-A1 Process for High Purity Anastrozole CYP19A1, CYP3A5, AURKC MAPK1 764/4885ALDH1A1 1933/4885TSHR 2290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.