SCHEMBL5899709

SCHEMBL5899709

CC(CC1CCCCC1)CC(OC(=O)N1CCOCC1)C(=O)NC1(C#N)CCN(C)CC1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSS P25774 20/20 0.67
CTSL P07711 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3892966 0.92 CTSS (0.72) CTSSCTSL
SCHEMBL3898442 0.87 CTSS (0.65) CTSSCTSL
SCHEMBL3895199 0.85 CTSS (0.55) CTSSCTSL
SCHEMBL3905719 0.84 CTSS (0.61) CTSSCTSL
SCHEMBL3900258 0.82 CTSS (0.59) CTSSCTSL
SCHEMBL3910482 0.82 CTSS (0.58) CTSSCTSL
SCHEMBL3894137 0.82 CTSS (0.58) CTSSCTSL
SCHEMBL3906537 0.81 CTSS (0.54) CTSSCTSL
SCHEMBL4019033 0.80 CTSS (0.63) CTSSCTSL
SCHEMBL6106855 0.80 CTSS (1.00) CTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6982263-B2 Nitriles useful as reversible inhibitors of cysteine proteases BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2006-01-03 US claimed