Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | CD38 | P28907 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901948 | 0.86 | CYP3A4 (0.43) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL4668543 | 0.83 | CYP3A4 (0.41) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL4592936 | 0.83 | CYP3A4 (0.41) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL4592937 | 0.81 | CYP3A4 (0.38) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL5901958 | 0.79 | CYP3A4 (0.46) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL13983524 | 0.78 | CYP3A4 (0.42) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL5901585 | 0.77 | CYP3A4 (0.62) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL7611919 | 0.77 | CYP3A4 (0.53) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL5177905 | 0.71 | HDAC6 (0.41) | CYP3A4CD38KCNH2CYP2C9CYP2D6 | |
| SCHEMBL13983541 | 0.71 | CYP3A4 (0.56) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060194969-A1 | 4-Substituted benzimidazoles and their uses as inhibitors of gastric secretion | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
| WO-2005096789-A2 | METHODS AND COMPOSITIONS FOR IMAGING AND BIOMEDICAL APPLICATIONS | GEORGIA TECH RESEARCH CORPORATION (US) | 2005-10-20 | — | — | WO | disclosed |
| EP-1575924-A1 | 4-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | ALTANA Pharma AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004054984-A1 | 4-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | ALTANA PHARMA AG (DE) | 2004-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194969-A1 | 4-Substituted benzimidazoles and their uses as inhibitors of gastric secretion | GIPR, VIP, SI | CYP3A4 21/4885CD38 4627/4885KCNH2 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.