Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.50 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20401146 | 0.88 | PTGES (0.48) | CHRM2CHRM1CHRM3NR1H4ALDH1A1 | |
| SCHEMBL29447610 | 0.88 | HPGD (0.57) | CHRM2CHRM1CHRM3NR1H4NPC1 | |
| SCHEMBL7473118 | 0.87 | LTB4R2 (0.49) | CHRM2CHRM1CHRM3AKT1NR1H4 | |
| SCHEMBL23912387 | 0.86 | NR1H4 (0.46) | CHRM2CHRM1CHRM3AKT1NR1H4 | |
| SCHEMBL4315970 | 0.86 | PTGES (0.54) | AKT1NR1H4HDAC3HDAC1HDAC2 | |
| SCHEMBL19922245 | 0.86 | AKT1 (0.47) | CHRM2CHRM1CHRM3AKT1NR1H4 | |
| SCHEMBL31434524 | 0.86 | AKT1 (0.44) | CHRM2CHRM1CHRM3AKT1NR1H4 | |
| SCHEMBL14809012 | 0.85 | BCL2A1 (0.48) | CHRM2CHRM1CHRM3ALDH1A1RAB9A | |
| SCHEMBL14809010 | 0.85 | BCL2A1 (0.48) | CHRM2CHRM1CHRM3ALDH1A1RAB9A | |
| SCHEMBL5906599 | 0.84 | AKT1 (0.42) | CHRM2CHRM1CHRM3AKT1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BAYER HEALTHCARE AG (DE) | 2006-04-27 | — | — | US | disclosed |
| EP-1575919-A1 | PHENYL OR HETEROARYL AMINO ALKANE DERIVATIVES AS IP RECEPTOR ANTAGONIST | Bayer HealthCare AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004043926-A1 | PHENYL OR HETEROARYL AMINO ALKANE DERIVATIVES AS IP RECEPTOR ANTAGONIST | BAYER HEALTHCARE AG (DE) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BPHL, HRH4, HRH2 | CHRM2 147/4885CHRM1 172/4885CHRM3 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.