Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | NPR3 | P17342 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906879 | 1.00 | KLK5 (0.46) | KLK5CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL5906929 | 0.85 | NPR3 (0.51) | KLK5CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL5906925 | 0.85 | NPR3 (0.51) | KLK5CYP2C9CYP2C19CYP3A4CYP2C8 | |
| SCHEMBL5906626 | 0.77 | CYP2C19 (0.41) | CYP2C9CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL5906627 | 0.77 | CYP2C19 (0.41) | CYP2C9CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL5906642 | 0.76 | ITGB1 (0.52) | CYP2C9CYP2C19CYP3A4ALDH1A1MEN1 | |
| SCHEMBL5906645 | 0.76 | ITGB1 (0.52) | CYP2C9CYP2C19CYP3A4ALDH1A1MEN1 | |
| SCHEMBL5906839 | 0.76 | ITGB1 (0.52) | CYP2C9CYP2C19CYP3A4ALDH1A1MEN1 | |
| SCHEMBL5906837 | 0.76 | TACR3 (0.47) | CYP2C19CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL5906861 | 0.76 | ELANE (0.48) | CYP2C19CYP3A4ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BAYER HEALTHCARE AG (DE) | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BPHL, HRH4, HRH2 | KLK5 524/4885CYP2C9 818/4885CYP2C19 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.