SCHEMBL5907751

SCHEMBL5907751

CC[Si](CC)(CC)CCOCN(c1ncc(Cl)nc1OC)S(=O)(=O)c1cccc(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1733387 0.91 CCR4 (0.52) CCR4
SCHEMBL1733157 0.86 CCR4 (0.51) CCR4
SCHEMBL1733005 0.82 CCR4 (0.53) CCR4
SCHEMBL1733421 0.80 CCR4 (0.56) CCR4
SCHEMBL4699938 0.79 CCR4 (0.39) CCR4
SCHEMBL1731807 0.78 CCR4 (0.42) CCR4
SCHEMBL1732964 0.78 CCR4 (0.57) CCR4
SCHEMBL1733274 0.78 CCR4 (0.52) CCR4
SCHEMBL1731829 0.77 CCR4 (0.56) CCR4
SCHEMBL4699972 0.75 CCR4 (0.41) CCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122195-A1 Sulphonamide compounds that modulate chemokine receptor activity (ccr4) ASTRAZENECA AB (SE) 2006-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122195-A1 Sulphonamide compounds that modulate chemokine receptor activity (ccr4) CCR4, CCR1, CCR3 CCR4 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.