SCHEMBL590787

SCHEMBL590787

Nc1ccccc1/N=N/c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.76
L3MBTL1 Q9Y468 4/20 0.76
RAB9A P51151 3/20 0.76
GAA P10253 2/20 0.76
MAPK1 P28482 6/20 0.62
TDP1 Q9NUW8 6/20 0.62
CYP3A4 P08684 5/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
TSHR P16473 3/20 0.62
ALDH1A1 P00352 2/20 0.62
TP53 P04637 2/20 0.62
MEN1 O00255 6/20 0.59
KMT2A Q03164 6/20 0.59
MAPT P10636 5/20 0.59
PKM P14618 2/20 0.56
HTT P42858 1/20 0.56
HBB P68871 2/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434865 1.00 NPC1 (0.76) NPC1L3MBTL1RAB9AGAAMAPK1
SCHEMBL29569176 1.00 NPC1 (0.76) NPC1L3MBTL1RAB9AGAAMAPK1
SCHEMBL29001132 1.00 NPC1 (0.76) NPC1L3MBTL1RAB9AGAAMAPK1
Hydrochloric Acid SCHEMBL11330488 0.98 NPC1 (0.73) NPC1L3MBTL1RAB9AGAAMAPK1
Ammonia Solution, Strong SCHEMBL27700309 0.98 NPC1 (0.73) NPC1L3MBTL1RAB9AGAAMAPK1
SCHEMBL18240065 0.87 NPC1 (1.00) NPC1L3MBTL1RAB9AGAAMAPK1
SCHEMBL1389297 0.87 NPC1 (1.00) NPC1L3MBTL1RAB9AGAAMAPK1
SCHEMBL30538675 0.87 NPC1 (1.00) NPC1L3MBTL1RAB9AGAAMAPK1
SCHEMBL2915566 0.87 NPC1 (1.00) NPC1L3MBTL1RAB9AGAAMAPK1
SCHEMBL11403966 0.87 MAPK1 (0.64) NPC1L3MBTL1RAB9AGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117123205-A Catalyst, preparation thereof and application thereof in methanation reaction of carbon dioxide 中国科学院大连化学物理研究所 2023-11-28 CN claimed
CN-115197131-A Azo 2-amino benzyl nicotinate derivative and preparation method and application thereof 华东理工大学 2022-10-18 CN claimed
EP-2686409-A1 KIT FOR MARKING AND/OR DETECTING ALTERATION OF FUEL AND ITS METHOD THEREOF Decipher PTE. Ltd. (SG) 2014-01-22 EP claimed
WO-2013020917-A1 Ophthalmologic composition comprising an aqueous solution of at least one viscoelastic polysaccharide CARL ZEISS MEDITEC AG (DE) 2013-02-14 WO claimed
WO-2012125120-A1 KIT FOR MARKING AND/OR DETECTING ALTERATION OF FUEL AND ITS METHOD THEREOF DECIPHER PTE. LTD. (SG) 2012-09-20 WO claimed
EP-2462441-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M Innovative Properties Company (US) 2012-06-13 EP claimed
WO-2011017317-A1 METHOD OF DETECTING OXIDES OF NITROGEN 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-02-10 WO claimed
WO-2007001908-A1 UV-C SENSITIVE COMPOSITION AND DOSIMETER CRYOVAC, INC. (US) 2007-01-04 WO claimed
US-20060289796-A1 UV-C sensitive composition and dosimeter CRYOVAC, INC. 2006-12-28 US claimed
EP-1150142-B1 COLOR POLARIZER WITH SUPPORT FOR LIQUID CRYSTAL PROJECTOR AND COLOR LIQUID CRYSTAL PROJECTOR NIPPON KAYAKU KK (JP) 2005-06-01 EP claimed
US-5990310-A REACTING A PHENYLAZOANILINE WITH A CYANURIC HALIDE AND REDUCING THE PHENYLAZOPHENYLAMINO-S-TRIAZINE TO PRODUCE AN AMINOANILINO-S-TRIAZINE FOLLOWED BY ALKYLATION; OZONE RESISTANCE; ANTISOILANTS; DISCOLORATION INHIBITION UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-11-23 US claimed
US-RE34877-E Red and blue dyes; improved thermal transferring; high absorption BASF AKTIENGESELLSCHAFT (DE) 1995-03-14 US claimed
EP-0441208-B1 Use of azo-dyes for thermal transfer printing BASF AG (DE) 1994-05-04 EP claimed
US-5158928-A Diffusion transfer BASF AKTIENGESELLSCHAFT (DE) 1992-10-27 US claimed
EP-0109172-A1 Novel substituted N-phenyl-N'benzoylureas and their use as insecticides and acaricides THE DOW CHEMICAL COMPANY (US) 1984-05-23 EP claimed
EP-0026088-B1 PHOTORESIST COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-11-23 EP claimed
US-4349619-A CONTAINING ANTIHALATION AGENTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US claimed
EP-0026088-A2 Photoresist compositions JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-01 EP claimed
US-4235957-A Thermal silver-dye bleach element and process EASTMAN KODAK COMPANY (US) 1980-11-25 US claimed
US-4191708-A Process for preparing and purifying p-phenylenediamine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-03-04 US claimed