SCHEMBL590835

SCHEMBL590835

CCCCCCCCCCCCCCCCCCNc1ccc(/C=C/c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.54
ALDH1A1 P00352 6/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
GLA P06280 2/20 0.53
KDM4E B2RXH2 1/20 0.50
PTGS2 P35354 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
GAA P10253 2/20 0.49
MGLL Q99685 1/20 0.49
APEX1 P27695 1/20 0.48
LMNA P02545 2/20 0.48
HTT P42858 1/20 0.48
HPGD P15428 1/20 0.48
ALOX12 P18054 1/20 0.48
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
APP P05067 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL590836 1.00 MAPT (0.54) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL9839382 1.00 MAPT (0.54) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL3476172 0.91 MAPT (0.64) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL9011397 0.91 MAPT (0.64) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL18932209 0.91 MAPT (0.64) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL3476080 0.91 MAPT (0.64) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL3476585 0.91 MAPT (0.64) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL10406550 0.91 MAPT (0.64) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL1046139 0.90 MAPT (0.66) MAPTALDH1A1SMN1; SMN2GLAKDM4E
SCHEMBL9847315 0.88 MAPT (0.60) MAPTALDH1A1SMN1; SMN2GLAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025017543-A1 A FLOATING PLANT FOR GENERATING HEAT AND/OR COOLING KRAĽ STEFAN (CZ) 2025-01-23 WO claimed
WO-2025010213-A2 MEDICAL CUTTING AND DRILL DEVICES HAVING STATIC COMPONENTS, RETRACTABLE SHEATHS, SENSORS, NAVIGATION COMPONENTS, WORKING BLADE BODIES, RAILS, STRUTS, CHANNELS FOR FLUID AND GAS FLOW, HAND-PIECE, ROBOTIC ARM ATTACHMENT CAPABILITIES, COMPUTING DEVICES, AND ASSOCIATED FEEDBACKS AND OUTPUTS Innovations 4 Surgery, LLC (US) 2025-01-09 WO claimed
WO-2024064253-A1 RICE CULTIVAR DESIGNATED 'CLL19' BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2024-03-28 WO claimed
CN-114341367-A Lung adenocarcinoma molecular typing and survival risk gene group, diagnosis product and application 上海善准生物科技有限公司 2022-04-12 CN claimed
EP-4283527-B1 OPTICAL ARTIFICIAL NEURAL NETWORK SYSTEM ELECTRONICS & TELECOMMUNICATIONS RES INST (KR) 2026-05-27 EP disclosed
EP-4719222-A1 ENDOSCOPIC SURGICAL INSTRUMENTS FOR APPLYING MULTIPLE CLIPS TO TISSUE Intuitive Surgical Operations, Inc. (US) 2026-04-08 EP disclosed
EP-4634952-A1 COMPACT ELECTRICAL CONTACTOR HAVING LOW CONTACT RESISTANCE Sonceboz Automotive S.A. (CH) 2025-10-22 EP disclosed
EP-4565989-A2 SEMIOTIC AND COMPOSITIONAL METHOD FOR ROBUST KNOWLEDGE REPRESENTATIONS AND REASONING AND APPARATUS THEREFOR Casadei, Stefano (US) 2025-06-11 EP disclosed
WO-2025059533-A1 CRISPR ENZYMES AND SYSTEMS THE BROAD INSTITUTE, INC. (US) 2025-03-20 WO disclosed
WO-2025050082-A2 NEAR FIELD COMMUNICATION TAG WITH ON/OFF CAPABILITY AIRA, INC. (US) 2025-03-06 WO disclosed
WO-2025049899-A1 SYSTEMS AND METHODS FOR IDENTIFYING TRUSTWORTHINESS OF DATA VINBERG LARS (US) 2025-03-06 WO disclosed
WO-2025042847-A1 PLASMID-HOST SYSTEMS DNA TWOPOINTO, INC. (US) 2025-02-27 WO disclosed
EP-2724156-B1 METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER AND AUTOIMMUNE DISEASE JACKSON LAB (US) 2017-08-16 EP disclosed
US-8754179-B2 Light activated shape memory co-polymers CORNERSTONE RESEARCH GROUP, INC. (US) 2014-06-17 US disclosed
US-20130184342-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER AND AUTOIMMUNE DISEASE THE JACKSON LABORATORY (US) 2013-07-18 US disclosed
US-8115182-B1 Personal and area self-indicating radiation alert dosimeter JP LABORATORIES INC. 2012-02-14 US disclosed
US-20080021166-A1 Light Activated Shape Memory Co-Polymers GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2008-01-24 US disclosed
EP-1799771-A2 LIGHT ACTIVATED SHAPE MEMORY CO-POLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2007-06-27 EP disclosed
US-7227158-B1 Stick-on self-indicating instant radiation dosimeter JP LABS, INC. (US) 2007-06-05 US disclosed
WO-2007001407-A2 LIGHT ACTIVATED SHAPE MEMORY CO-POLYMERS CORNERSTONE RESEARCH GROUP, INC. (US) 2007-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130184342-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER AND AUTOIMMUNE DISEASE BAK1, SSB, MRE11 MAPT 3931/4885ALDH1A1 3148/4885SMN1; SMN2 2316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.