Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476585 | 1.00 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL10406550 | 1.00 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL18932209 | 1.00 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL3476080 | 1.00 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL3476172 | 1.00 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL1046139 | 0.98 | MAPT (0.66) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL9651956 | 0.93 | MAPT (0.68) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL10877789 | 0.91 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL590835 | 0.91 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL14117517 | 0.91 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2GLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510224-A | HYDROPHOBIC SENSITIZER | SEIKO INSTRUMENTS INC. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5292458-A | Containing polymerizable monomer and initiator | SEIKO INSTRUMENTS INC. (JP) | 1994-03-08 | — | — | US | disclosed |