Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914156 | 0.87 | HTR7 (0.46) | CCNT1CCNA2CDK2CDK9HTR7 | |
| SCHEMBL5914231 | 0.86 | CYP1A2 (0.45) | CCNT1CCNA2CDK2CDK9HTR7 | |
| SCHEMBL5914059 | 0.85 | HTR7 (0.43) | CCNT1CCNA2CDK2CDK9HTR7 | |
| SCHEMBL5913829 | 0.83 | MAPK14 (0.45) | CCNT1CCNA2CDK2CDK9HTR7 | |
| SCHEMBL5913939 | 0.81 | HTR7 (0.44) | CCNT1CCNA2CDK2CDK9HTR7 | |
| SCHEMBL5914395 | 0.81 | CYP1A2 (0.55) | CCNT1CCNA2CDK2CDK9OGA | |
| SCHEMBL5913967 | 0.80 | HTR7 (0.48) | CCNT1CCNA2CDK2CDK9HTR7 | |
| SCHEMBL5913889 | 0.80 | MAPT (0.43) | CCNT1CCNA2CDK2CDK9HTR7 | |
| SCHEMBL5914257 | 0.78 | MAPT (0.45) | CCNT1CCNA2CDK2CDK9HTR7 | |
| SCHEMBL5914306 | 0.76 | MKNK1 (0.47) | CCNT1CCNA2CDK2CDK9HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060069110-A1 | Substituted heterocyclic compounds and methods of use | AMGEN INC. | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069110-A1 | Substituted heterocyclic compounds and methods of use | MAPT, MYLK2, IAPP | CCNT1 369/4885CCNA2 2516/4885CDK2 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.