Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 10/20 | 0.66 |
| ▸ | BCHE | P06276 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | XDH | P47989 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | P4HB | P07237 | 1/20 | 0.63 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.60 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915672 | 1.00 | F3 (0.69) | F3MAOBBCHEMAPTMAOA | |
| SCHEMBL5915808 | 1.00 | F3 (0.69) | F3MAOBBCHEMAPTMAOA | |
| SCHEMBL5915693 | 0.88 | F3 (0.63) | F3MAOBBCHEMAPTMAOA | |
| SCHEMBL5915461 | 0.88 | F3 (0.63) | F3MAOBBCHEMAPTMAOA | |
| SCHEMBL5915464 | 0.88 | F3 (0.63) | F3MAOBBCHEMAPTMAOA | |
| SCHEMBL5915335 | 0.87 | F3 (0.73) | F3MAOBBCHEMAPTMAOA | |
| SCHEMBL5915802 | 0.87 | F3 (0.73) | F3MAOBBCHEMAPTMAOA | |
| SCHEMBL5915334 | 0.87 | F3 (0.73) | F3MAOBBCHEMAPTMAOA | |
| SCHEMBL6141085 | 0.86 | BCHE (0.59) | F3MAOBBCHEMAPTMAOA | |
| 4,4'-Dimethoxychalcone SCHEMBL978243 | 0.83 | F3 (1.00) | F3MAOBBCHEMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052600-A1 | Amino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-03-09 | — | — | US | claimed |
| US-20060052600-A1 | Amino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-03-09 | — | — | US | disclosed |