SCHEMBL5916613

SCHEMBL5916613

CCO[Si](CCCCCN(CC)C(=O)O)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
CNR2 P34972 1/20 0.32
MGLL Q99685 1/20 0.32
ALDH1A1 P00352 1/20 0.30
NPC1 O15118 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916562 1.00 LMNA (0.34) LMNACA12CA1CA9CNR2
SCHEMBL5916941 0.98 LMNA (0.35) LMNACA12CA1CA9CNR2
SCHEMBL443029 0.93 LMNA (0.36) LMNACA12CA1CA9ALDH1A1
SCHEMBL5916981 0.88 LMNA (0.31) LMNACA12CA1CA9
SCHEMBL5916900 0.86 LMNA (0.34) LMNAALDH1A1
SCHEMBL7572215 0.85 LMNA (0.33) LMNACA12CA1CA9CNR2
SCHEMBL5916600 0.85 LMNA (0.33) LMNACA12CA1CA9CNR2
SCHEMBL5916965 0.85 LMNA (0.35) LMNACA12CA1CA9CNR2
SCHEMBL5916711 0.85 LMNA (0.35) LMNACA12CA1CA9CNR2
SCHEMBL4359796 0.84 CA12 (0.31) CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed
EP-1328586-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF Henkel Kommanditgesellschaft auf Aktien (DE) 2003-07-23 EP disclosed
WO-2002050020-A1 METHOD FOR PRODUCING ISOCYANATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-27 WO disclosed
WO-2002034838-A1 POLYMERS WITH UREA GROUPS AND SILYL GROUPS AND PRODUCTION AND USE THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-05-02 WO disclosed