Diphenylether

Diphenylether

SCHEMBL5918239

O=C(O)CC(C(=O)O)S(=O)(=O)O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 2/20 0.44
MMP12 P39900 1/20 0.44
FFAR1 O14842 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43
LTA4H P09960 2/20 0.42
MMP9 P14780 1/20 0.41
MMP2 P08253 1/20 0.41
MMP3 P08254 1/20 0.41
EPOR P19235 1/20 0.41
SRC P12931 1/20 0.41
PTGS1 P23219 1/20 0.41
SRD5A2 P31213 1/20 0.41
TSHR P16473 1/20 0.40
PGR P06401 1/20 0.40
SOS1 Q07889 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL28174492 0.94 MMP2 (0.43) MMP13MMP12FFAR1SMN1; SMN2PPARG
Diphenylether SCHEMBL28785735 0.90 AKR1C3 (0.39) MMP13MMP12FFAR1SMN1; SMN2PPARG
Naphthalene SCHEMBL5839060 0.84 SRC (0.44) SRCTSHR
Phenol SCHEMBL3671181 0.83 SRC (0.44) SRCTSHRCA1CA2CA9
Aniline SCHEMBL2803039 0.81 POLB (0.44) SMN1; SMN2SRCTSHR
Naphthalene SCHEMBL15322158 0.81 SRC (0.42) SRCTSHR
Phenol SCHEMBL27821795 0.81 SRC (0.43) SRCTSHRCA1CA2CA9
SCHEMBL18140728 0.81 SRC (0.42) SRCTSHR
SCHEMBL18141518 0.81 SRC (0.42) SRCTSHR
SCHEMBL1592208 0.81 ATM (0.42) MMP13MMP12FFAR1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11578028-B2 Surfactant composition DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2023-02-14 US claimed
CN-109790369-B Surfactant composition 第一工业制药株式会社 2022-01-04 CN claimed
WO-2021198866-A1 BLUE CATHODIC ELECTRODEPOSITION (CED) COATING COMPOSITION KANSAI NEROLAC PAINTS LIMITED (IN) 2021-10-07 WO claimed
CN-109890495-B Surfactant composition 第一工业制药株式会社 2021-04-20 CN claimed
US-10940453-B2 Surfactant composition DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2021-03-09 US claimed
US-20200331830-A1 SURFACTANT COMPOSITION DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2020-10-22 US claimed
US-20190217265-A1 SURFACTANT COMPOSITION DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2019-07-18 US claimed
CN-115075051-A Rosin sizing agent for papermaking and paper 荒川化学工业株式会社 2022-09-20 CN disclosed
CN-109790369-B Surfactant composition 第一工业制药株式会社 2022-01-04 CN disclosed
US-11155700-B2 Tire puncture sealant THE YOKOHAMA RUBBER CO., LTD. (JP) 2021-10-26 US disclosed
WO-2021198866-A1 BLUE CATHODIC ELECTRODEPOSITION (CED) COATING COMPOSITION KANSAI NEROLAC PAINTS LIMITED (IN) 2021-10-07 WO disclosed
CN-109890495-B Surfactant composition 第一工业制药株式会社 2021-04-20 CN disclosed
US-20200040164-A1 TIRE PUNCTURE SEALANT THE YOKOHAMA RUBBER CO., LTD. (JP) 2020-02-06 US disclosed
CN-101735506-A Sealant composition for repairing a punctured tire YOKOHAMA RUBBER CO LTD 2010-06-16 CN disclosed
US-20060183832-A1 Plasticizer for polyester resin KAO CORPORATION (JP) 2006-08-17 US disclosed
EP-1403322-A1 PLASTICIZER FOR POLYESTER RESIN Kao Corporation (JP) 2004-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11578028-B2 Surfactant composition CHRM1, DEGS1, ASH2L MMP13 2975/4885MMP12 2551/4885FFAR1 318/4885
US-20200331830-A1 SURFACTANT COMPOSITION CHRM1, DEGS1, ASH2L MMP13 2975/4885MMP12 2551/4885FFAR1 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.