Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 13/20 | 1.00 |
| ▸ | DRD2 | P14416 | 6/20 | 0.72 |
| ▸ | DRD4 | P21917 | 6/20 | 0.72 |
| ▸ | DRD3 | P35462 | 5/20 | 0.72 |
| ▸ | HRH1 | P35367 | 3/20 | 0.61 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | HTR3B | O95264 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142771 | 0.86 | CHRM1 (0.76) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL14365315 | 0.84 | DRD4 (0.76) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL3413080 | 0.84 | CHRM1 (1.00) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL29470861 | 0.84 | DRD2 (1.00) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL141020 | 0.84 | DRD2 (1.00) | CHRM1DRD2DRD4DRD3HRH1 | |
| Isoclozapine SCHEMBL140207 | 0.83 | CHRM1 (1.00) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL9094636 | 0.83 | CHRM1 (1.00) | CHRM1DRD2DRD4DRD3HRH1 | |
| Isoclozapine SCHEMBL29822724 | 0.83 | CHRM1 (1.00) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL5557955 | 0.81 | DRD2 (0.74) | CHRM1DRD2DRD4DRD3HRH1 | |
| SCHEMBL5563810 | 0.81 | CHRM1 (0.70) | CHRM1DRD2DRD4DRD3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060069083-A1 | Pesticidal dibenzo(hetero)azepine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-30 | — | — | US | disclosed |
| EP-1578198-A1 | PESTICIDAL DIBENZO(HETERO)AZEPINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004056182-A1 | PESTICIDAL DIBENZO(HETERO)AZEPINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069083-A1 | Pesticidal dibenzo(hetero)azepine derivatives | GLRA3, DDT, NR2E1 | CHRM1 270/4885DRD2 84/4885DRD4 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.