Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.52 |
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5921680 | 1.00 | GAA (0.65) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL5921805 | 0.90 | GPR132 (0.62) | GPR132PTPN1 | |
| SCHEMBL5921800 | 0.90 | GPR132 (0.62) | GPR132PTPN1 | |
| SCHEMBL5921641 | 0.88 | GAA (0.67) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL5921637 | 0.88 | GAA (0.67) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL5921742 | 0.86 | GAA (0.64) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL5921740 | 0.86 | GAA (0.64) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL1123370 | 0.83 | GAA (0.73) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL1123642 | 0.83 | GAA (0.67) | GAARAB9AALDH1A1LMNALNPEP | |
| SCHEMBL5921780 | 0.82 | GAA (0.59) | GAARAB9AALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166989-A1 | 2-naphthamide derivatives | BAYER HEALTHCARE AG (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1515941-A1 | 2-NAPHTHAMIDE DERIVATIVES | Bayer HealthCare AG (DE) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003106402-A1 | 2-NAPHTAMIDE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166989-A1 | 2-naphthamide derivatives | BPHL, F2RL1, HRH2 | GAA 1846/4885RAB9A 2535/4885ALDH1A1 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.