Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5923925 | 0.86 | TAS1R3 (0.68) | MAPK1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL19612837 | 0.85 | MAPK1 (0.52) | MAPK1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL5923952 | 0.83 | TAS1R3 (0.61) | MAPK1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL10363346 | 0.80 | MAPK1 (0.65) | MAPK1MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL11350134 | 0.79 | MEN1 (0.71) | MAPK1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11419256 | 0.77 | MEN1 (0.60) | MAPK1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Benzene SCHEMBL11581029 | 0.77 | MAPK1 (0.66) | MAPK1MEN1KMT2AUSP2SMN1; SMN2 | |
| SCHEMBL11418838 | 0.76 | MEN1 (0.64) | MAPK1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5923935 | 0.75 | TAS1R3 (0.70) | MAPK1TAS1R3TAS1R1USP2SMN1; SMN2 | |
| SCHEMBL11583197 | 0.74 | MAPK1 (0.59) | MAPK1MEN1KMT2AUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |