Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 17/20 | 0.81 |
| ▸ | TAS1R1 | Q7RTX1 | 17/20 | 0.81 |
| ▸ | TAS1R2 | Q8TE23 | 15/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5923912 | 1.00 | TAS1R3 (0.81) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B2 | |
| SCHEMBL701253 | 0.89 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B2 | |
| SCHEMBL701932 | 0.87 | TAS1R3 (0.80) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL3730549 | 0.87 | TAS1R3 (0.80) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL5276430 | 0.85 | TAS1R3 (0.72) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL701854 | 0.83 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL701855 | 0.83 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL5319909 | 0.81 | TAS1R3 (0.74) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL20860976 | 0.80 | TAS1R3 (0.93) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL5923958 | 0.80 | TAS1R3 (0.84) | TAS1R3TAS1R1TAS1R2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |