Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.63 |
| ▸ | TAS1R2 | Q8TE23 | 8/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5923933 | 1.00 | TAS1R3 (0.63) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL5923936 | 1.00 | TAS1R3 (0.63) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL5923938 | 1.00 | TAS1R3 (0.63) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL13928024 | 0.82 | TAS1R3 (0.81) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL4175750 | 0.82 | TAS1R3 (0.81) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL4175061 | 0.82 | TAS1R3 (0.81) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL702725 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL700841 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL700840 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 | |
| SCHEMBL20662892 | 0.76 | TAS1R3 (0.89) | TAS1R3TAS1R1TAS1R2PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |