Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.57 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.55 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | ALPG | P10696 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL592722 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4567104 | 0.98 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3748597 | 0.98 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28621623 | 0.96 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28621621 | 0.96 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| Iodide SCHEMBL7034942 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| Iodide SCHEMBL7034947 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13645991 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7036731 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7036729 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715623-A | Photothermal conversion eutectic material and preparation method and application thereof | 汕头大学 | 2023-09-08 | — | — | CN | claimed |
| US-20250241968-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-07-31 | — | — | US | disclosed |
| US-20250043326-A1 | NEUROTRANSMITTER TRANSPORT IN PROBIOTICS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2025-02-06 | — | — | US | disclosed |
| US-12152270-B2 | Neurotransmitter transport in probiotics | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2024-11-26 | — | — | US | disclosed |
| WO-2024050560-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-03-07 | — | — | WO | disclosed |
| US-20220125952-A1 | DELIVERY OF POLYNUCLEOTIDES USING RECOMBINANT AAV9 | NATIONWIDE CHILDREN'S HOSPITAL, INC. | 2022-04-28 | — | — | US | disclosed |
| US-11219696-B2 | Delivery of polynucleotides using recombinant AAV9 | NATIONWIDE CHILDREN'S HOSPITAL (US) | 2022-01-11 | — | — | US | disclosed |
| US-11150358-B2 | Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry | RIKEN (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20210155968-A1 | NEUROTRANSMITTER TRANSPORT IN PROBIOTICS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2021-05-27 | — | — | US | disclosed |
| US-10941433-B2 | Neurotransmitter transport in probiotics | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-03-09 | — | — | US | disclosed |
| US-6812268-B2 | Methods for material fabrication utilizing the polymerization of nanoparticles | SCIENCE APPLICATIONS INTERNATIONAL CORPORATION | 2004-11-02 | — | — | US | disclosed |
| WO-2004077097-A2 | SELF-INDICATING RADIATION ALERT DOSIMETER | JP LABORATORIES INC. (US) | 2004-09-10 | — | — | WO | disclosed |
| US-20040115703-A1 | Rapid assays for neurotransmitter transporters | VANDERBILT UNIVERSITY | 2004-06-17 | — | — | US | disclosed |
| EP-1418938-A1 | BONT/E OR SNAP-25E FOR TREATING BOTULINUM TOXIN A OR C1 POISONING AND INHIBITING MUSCLE CONTRACTION | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2004-05-19 | — | — | EP | disclosed |
| US-20030083401-A1 | Methods for material fabrication utilizing the polymerization of nanoparticles | LEIDOS, INC. | 2003-05-01 | — | — | US | disclosed |
| US-20030022105-A1 | TWO -PHOTON UPCONVERTING DYES AND APPLICATIONS | PRASAD PARAS N (US) | 2003-01-30 | — | — | US | disclosed |
| WO-2002089834-A1 | BONT/E OR SNAP-25E FOR TREATING BOTULINUM TOXIN A OR C1 POISONING AND INHIBITING MUSCLE CONTRACTION | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2002-11-14 | — | — | WO | disclosed |
| US-6402037-B1 | Two-photon upconverting dyes and applications | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-06-11 | — | — | US | disclosed |
| US-6067158-A | Method for detecting abnormal morphology of erythrocytes | SYSMEX CORPORATION (JP) | 2000-05-23 | — | — | US | disclosed |
| WO-1997009043-A9 | TWO-PHOTON UPCONVERTING DYES AND APPLICATIONS | — | 1997-09-18 | — | — | WO | disclosed |