Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | CTSA | P10619 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5927134 | 0.94 | KCNA3 (0.44) | EGLN2EGLN1ALDH1A1GAAHPGD | |
| SCHEMBL5926984 | 0.94 | FFAR1 (0.46) | EGLN2EGLN1CTSAHTTL3MBTL1 | |
| SCHEMBL5927214 | 0.92 | CYP26A1 (0.44) | EGLN2EGLN1CTSAALDH1A1GAA | |
| SCHEMBL5926942 | 0.89 | CTSA (0.41) | EGLN2EGLN1CTSACYP26A1 | |
| SCHEMBL5926305 | 0.89 | CYP26A1 (0.44) | EGLN2EGLN1CTSACYP26A1PTGER4 | |
| SCHEMBL5926905 | 0.89 | FFAR1 (0.42) | EGLN2EGLN1CTSACYP26A1UTS2R | |
| SCHEMBL5926750 | 0.87 | SERPINE1 (0.56) | EGLN2EGLN1CTSAHPGDL3MBTL1 | |
| SCHEMBL5926778 | 0.87 | THRB (0.42) | EGLN2EGLN1CTSAATMITGB1 | |
| SCHEMBL5926944 | 0.87 | CYP26A1 (0.46) | EGLN2EGLN1CTSAITGB1ITGA4 | |
| SCHEMBL5926299 | 0.86 | CTSA (0.43) | EGLN2EGLN1CTSAHTTCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | EGLN2 636/4885EGLN1 872/4885CTSA 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.