Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 14/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | POLB | P06746 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | BCHE | P06276 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | PPARG | P37231 | 2/20 | 0.70 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL31277202 | 1.00 | ACHE (1.00) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| Iodide SCHEMBL592814 | 1.00 | ACHE (1.00) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL5675231 | 0.99 | ACHE (0.97) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL5675236 | 0.99 | ACHE (0.97) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| Perchlorate SCHEMBL4886007 | 0.93 | ACHE (0.87) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL8336760 | 0.86 | ACHE (0.76) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL8336762 | 0.86 | ACHE (0.76) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL14007198 | 0.85 | ACHE (0.74) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| Iodide SCHEMBL5088258 | 0.85 | ACHE (1.00) | ACHEKMT2APOLBMEN1SMN1; SMN2 | |
| Iodide SCHEMBL5088261 | 0.85 | ACHE (1.00) | ACHEKMT2APOLBMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210222226-A1 | METHODS OF MEASURING ENZYME ACTIVITY IN COATING COMPOSTIONS | BASF SE (DE) | 2021-07-22 | — | — | US | claimed |
| EP-3814518-A1 | METHODS OF MEASURING ENZYME ACTIVITY IN COATING COMPOSITIONS | BASF SE (DE) | 2021-05-05 | — | — | EP | claimed |
| WO-2019104300-A1 | SYSTEM FOR VIEWING LUMINOUS BUBBLES AND BUBBLE FORMING COMPOSITION | COWAN, Cathy (US) | 2019-05-31 | — | — | WO | claimed |
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | claimed |
| US-6770102-B1 | AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-08-03 | — | — | US | claimed |
| EP-1200051-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | claimed |
| WO-2001013866-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-03-01 | — | — | WO | claimed |
| US-5403744-A | Colorimetric analysis using metachromatic dye, pH indicator dye, polyelectrolytes with anionic sites to bind with dyes; for testing urine, blood | MILES INC. (US) | 1995-04-04 | — | — | US | claimed |
| US-11150358-B2 | Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry | RIKEN (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20210222226-A1 | METHODS OF MEASURING ENZYME ACTIVITY IN COATING COMPOSTIONS | BASF SE (DE) | 2021-07-22 | — | — | US | disclosed |
| EP-3814518-A1 | METHODS OF MEASURING ENZYME ACTIVITY IN COATING COMPOSITIONS | BASF SE (DE) | 2021-05-05 | — | — | EP | disclosed |
| US-20200333474-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | RIKEN (JP) | 2020-10-22 | — | — | US | disclosed |
| EP-3686632-A1 | RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY | Riken (JP) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019104300-A1 | SYSTEM FOR VIEWING LUMINOUS BUBBLES AND BUBBLE FORMING COMPOSITION | COWAN, Cathy (US) | 2019-05-31 | — | — | WO | disclosed |
| US-20040149026-A1 | Method and devices for quantitative evaluation of coatings | GENERAL ELECTRIC COMPANY | 2004-08-05 | — | — | US | disclosed |
| US-6770102-B1 | AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-08-03 | — | — | US | disclosed |
| EP-1200051-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001013866-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-03-01 | — | — | WO | disclosed |
| US-5403744-A | Colorimetric analysis using metachromatic dye, pH indicator dye, polyelectrolytes with anionic sites to bind with dyes; for testing urine, blood | MILES INC. (US) | 1995-04-04 | — | — | US | disclosed |
| EP-0611966-A1 | Method, composition and device for measuring the ionic strength or specific gravity of a test sample | Bayer Corporation (US) | 1994-08-24 | — | — | EP | disclosed |