Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928992 | 0.85 | CYP3A4 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL5929059 | 0.83 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL5929030 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1 | |
| SCHEMBL5929189 | 0.82 | KMT2A (0.36) | KDM4EALDH1A1 | |
| SCHEMBL5929124 | 0.82 | BCHE (0.37) | KDM4EALDH1A1 | |
| SCHEMBL5928975 | 0.80 | CNR1 (0.37) | KDM4ECNR1 | |
| SCHEMBL5929060 | 0.74 | CYP3A4 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL5929331 | 0.73 | ALDH1A1 (0.33) | KDM4EALDH1A1CNR1SLC6A9 | |
| SCHEMBL5929248 | 0.72 | KDM4E (0.33) | KDM4EALDH1A1CNR1 | |
| SCHEMBL5929012 | 0.72 | POLB (0.38) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154917-A1 | Substituted (heterocycloalkyl)methyl azole derivatives as c5a receptor modulators | NEUROGEN CORPORATION (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154917-A1 | Substituted (heterocycloalkyl)methyl azole derivatives as c5a receptor modulators | C5AR1, C5AR2, C3AR1 | KDM4E 1762/4885ALDH1A1 3884/4885CNR1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.