Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | CFB | P00751 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929122 | 0.85 | KMT2A (0.41) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL5929219 | 0.80 | OPRK1 (0.40) | CFBALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL5929363 | 0.80 | KMT2A (0.39) | CFBALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL5929135 | 0.80 | GAA (0.41) | CFBALDH1A1KMT2AKDM4EMAOB | |
| SCHEMBL5929073 | 0.79 | KMT2A (0.40) | ALDH1A1KMT2ANPSR1MEN1HTT | |
| SCHEMBL5928924 | 0.78 | KMT2A (0.37) | CFBALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL5929123 | 0.76 | POLB (0.40) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL5929141 | 0.76 | KMT2A (0.38) | CFBALDH1A1LMNAKMT2AHTT | |
| SCHEMBL5929300 | 0.75 | KDM4E (0.41) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL5929058 | 0.75 | GAA (0.43) | ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154917-A1 | Substituted (heterocycloalkyl)methyl azole derivatives as c5a receptor modulators | NEUROGEN CORPORATION (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154917-A1 | Substituted (heterocycloalkyl)methyl azole derivatives as c5a receptor modulators | C5AR1, C5AR2, C3AR1 | SLC2A1 4143/4885GNRHR 748/4885CFB 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.