Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CFB | P00751 | 6/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929211 | 0.87 | OPRK1 (0.43) | PARP1OPRK1CFBPOLBKDM4E | |
| SCHEMBL5929134 | 0.85 | GAA (0.39) | CFBPDCD1CD274 | |
| SCHEMBL5929306 | 0.84 | C5AR1 (0.44) | LMNAPOLBKDM4EALDH1A1MAPK1 | |
| SCHEMBL5928944 | 0.83 | PARP1 (0.42) | PARP1OPRK1CFBPARP2CYP3A4 | |
| SCHEMBL5929002 | 0.82 | CD274 (0.36) | CYP3A4KCNH2PDCD1CD274KDM4E | |
| SCHEMBL5929082 | 0.80 | OPRK1 (0.37) | OPRK1CFBCYP3A4LMNAKDM4E | |
| SCHEMBL5929232 | 0.79 | PARP1 (0.40) | PARP1OPRK1CFBCYP3A4CYP2D6 | |
| SCHEMBL5929363 | 0.78 | KMT2A (0.39) | OPRK1CFBLMNAOPRD1KDM4E | |
| SCHEMBL5929135 | 0.77 | GAA (0.41) | CFBPDCD1CD274KDM4EALDH1A1 | |
| SCHEMBL5928899 | 0.76 | GAA (0.40) | CFBCYP3A4POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154917-A1 | Substituted (heterocycloalkyl)methyl azole derivatives as c5a receptor modulators | NEUROGEN CORPORATION (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154917-A1 | Substituted (heterocycloalkyl)methyl azole derivatives as c5a receptor modulators | C5AR1, C5AR2, C3AR1 | PARP1 3644/4885OPRK1 523/4885CFB 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.