SCHEMBL593172

SCHEMBL593172

CC(=O)CC(=O)Nc1ccc(NC(=O)CC(C)=O)cc1

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.74
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69
CA4 P22748 1/20 0.69
CA7 P43166 1/20 0.69
POLB P06746 4/20 0.67
TSHR P16473 1/20 0.67
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
KDM4E B2RXH2 1/20 0.63
ALDH1A1 P00352 1/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2C19 P33261 1/20 0.63
HIF1A Q16665 1/20 0.63
HTT P42858 2/20 0.52
TP53 P04637 1/20 0.52
LMNA P02545 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6204592 0.93 MAPT (0.67) MAPTCA1CA2CA4CA7
SCHEMBL14075487 0.91 MAPT (0.65) MAPTCA1CA2CA4CA7
SCHEMBL56594 0.91 POLB (0.80) MAPTCA1CA2CA4CA7
SCHEMBL9341609 0.91 MAPT (0.65) MAPTCA1CA2CA4CA7
SCHEMBL10603962 0.89 POLB (0.67) MAPTCA1CA2CA4CA7
SCHEMBL11575897 0.89 ALDH1A1 (0.62) MAPTCA1CA2CA4CA7
SCHEMBL31570085 0.89 MAPT (0.64) MAPTCA1CA2CA4CA7
SCHEMBL4671464 0.89 MAPT (0.62) MAPTCA1CA2CA4CA7
SCHEMBL7094502 0.89 MAPT (0.62) MAPTCA1CA2CA4CA7
SCHEMBL1225424 0.89 KMT2A (0.77) MAPTCA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9740126-B2 Electrostatic charge image developing toner, electrostatic charge image developer, and toner cartridge FUJI XEROX CO., LTD. (JP) 2017-08-22 US claimed
US-20170199477-A1 ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, ELECTROSTATIC CHARGE IMAGE DEVELOPER, AND TONER CARTRIDGE FUJI XEROX CO., LTD. (JP) 2017-07-13 US claimed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
EP-0581245-B1 Water-insoluble azo colouring agents CLARIANT GMBH (DE) 1998-12-23 EP claimed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0587021-B1 Use of preparations of azo-pigments containing solvents for intaglio printing and flexographic printing on packaging HOECHST AG (DE) 1995-08-16 EP claimed
US-5428136-A Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component HOECHST AG (DE) 1995-06-27 US claimed
US-5352281-A Containing nonionic surfactant with specified cloud point HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-04 US claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
EP-0587021-A1 Use of preparations of azo-pigments containing solvents for intaglio printing and flexographic printing on packaging HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-16 EP claimed
EP-0581245-A1 Water-insoluble azo colouring agents HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-02 EP claimed
JP-6228448-A None JP disclosed
EP-3233978-B1 COMPOSITIONS COMPRISING A POLYMERIC NETWORK UNIV GENT (BE) 2021-03-03 EP disclosed
EP-3233978-B1 COMPOSITIONS COMPRISING A POLYMERIC NETWORK UNIV GENT (BE) 2021-03-03 EP disclosed
US-10246548-B2 Compositions comprising a polymeric network UNIVERSITEIT GENT (BE) 2019-04-02 US disclosed
US-4065500-A Water-soluble quaternary ammonium azo dyestuffs STERLING DRUG INC. (US) 1977-12-27 US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 US disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3935182-A Water-soluble quaternary ammonium heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10246548-B2 Compositions comprising a polymeric network CHRNA5, CHRNA1, CHRM1 MAPT 3072/4885CA1 1549/4885CA2 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.