SCHEMBL593272

SCHEMBL593272

O=C(CO)Oc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.58
ELANE P08246 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
ALOX15 P16050 2/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ALDH1A1 P00352 4/20 0.45
MAPT P10636 3/20 0.45
KMT2A Q03164 4/20 0.44
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
RECQL P46063 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
NSD2 O96028 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27396289 0.98 CYP19A1 (0.56) CYP19A1ELANETDP1L3MBTL1ATM
Cyclohexane SCHEMBL6052077 0.94 CYP19A1 (0.53) CYP19A1ELANETDP1L3MBTL1ATM
SCHEMBL1931453 0.87 KMT2A (0.54) CYP19A1ELANEHPGDHSD17B10ALDH1A1
SCHEMBL7564565 0.87 ASAH1 (0.55) CYP19A1ELANEALDH1A1MAPTKMT2A
SCHEMBL3404040 0.84 PPARG (0.54) CYP19A1ELANEL3MBTL1HPGDKMT2A
SCHEMBL43742 0.83 KMT2A (0.61) CYP19A1ELANETDP1L3MBTL1ATM
SCHEMBL153387 0.83 CYP19A1 (0.55) CYP19A1ELANETDP1L3MBTL1ATM
SCHEMBL538524 0.82 CYP19A1 (0.76) CYP19A1L3MBTL1HPGDALDH1A1KMT2A
SCHEMBL6306550 0.82 PRSS1 (0.51) CYP19A1ELANETDP1L3MBTL1ATM
SCHEMBL231450 0.81 CYP19A1 (0.53) CYP19A1ELANETDP1L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350290-A Method for preparing 1, 4-dioxane-2-ketone from ethylene carbonate 青岛科技大学 2025-01-24 CN claimed
CN-119350289-A Method for preparing high-purity 1, 4-dioxane-2-ketone at low cost 青岛科技大学 2025-01-24 CN claimed
CN-109384663-B Synthesis method of 4-iodophenoxyacetic acid 国药集团化学试剂有限公司 2021-08-03 CN claimed
CN-108929226-B Method for preparing benzoyl formate derivative 广东工业大学 2021-05-28 CN claimed
EP-3168215-B1 PROCESS FOR PREPARATION OF BARNIDIPINE USV PRIVATE LTD (IN) 2020-05-20 EP claimed
US-20180246059-A1 Electrochemical Tongue UNIVERSITY OF MASSACHUSETTS 2018-08-30 US claimed
EP-3168215-A2 PROCESS FOR PREPARATION OF BARNIDIPINE USV Private Limited (IN) 2017-05-17 EP claimed
CN-102892765-B Cyclohexylamine derivatives having beta 2 adrenergic agonist and M3 muscarinic antagonist activity ALMIRALL SA 2015-04-29 CN claimed
CN-102834479-B Polishing agent for polishing copper and polishing method using the same HITACHI CHEMICAL CO LTD 2015-02-18 CN claimed
CN-101180379-B Dihydroxy enol compounds used in chemical mechanical polishing compositions having metal ion oxidizers AIR PROD & CHEM 2013-07-24 CN claimed
US-5554597-A Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging TRISTRATA INC (US) 1996-09-10 US claimed
US-5554654-A COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND TRISTRATA INC (US) 1996-09-10 US claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
EP-0273202-B1 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. SCOTT EUGENE J VAN (US) 1995-06-21 EP claimed
EP-0599819-A2 Additives enhancing topical actions of therapeutic agents Van Scott, Eugene J., Dr. (US) 1994-06-01 EP claimed
EP-0413528-A1 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use Yu, Ruey J., Dr. (US) 1991-02-20 EP claimed
EP-0302473-A2 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells Bristol-Myers Squibb Company (US) 1989-02-08 EP claimed
EP-0098743-B1 PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE Yu, Ruey J., Dr. (US) 1988-09-28 EP claimed
EP-0273202-A2 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. Van Scott, Eugene J., Dr. (US) 1988-07-06 EP claimed
EP-0098743-A1 Phenyl alpha-acyloxyacetamide derivates and their therapeutic use Yu, Ruey J., Dr. (US) 1984-01-18 EP claimed